Sciarrillo R - Search Results

1

NF-κB drives acquired resistance to a novel mutant-selective EGFR inhibitor.

Galvani E, Sun J, Leon LG, Sciarrillo R, Narayan RS, Sjin RT, Lee K, Ohashi K, Heideman DA, Alfieri RR, Heynen GJ, Bernards R, Smit EF, Pao W, Peters GJ, Giovannetti E. Galvani E, et al. Among authors: sciarrillo r. Oncotarget. 2015 Dec 15;6(40):42717-32. doi: 10.18632/oncotarget.3956. Oncotarget. 2015. PMID: 26015408 Free PMC article.

2

Molecular mechanisms and modulation of key pathways underlying the synergistic interaction of sorafenib with erlotinib in non-small-cell-lung cancer (NSCLC) cells.

Giovannetti E, Labots M, Dekker H, Galvani E, Lind JS, Sciarrillo R, Honeywell R, Smit EF, Verheul HM, Peters GJ. Giovannetti E, et al. Among authors: sciarrillo r. Curr Pharm Des. 2013;19(5):927-39. Curr Pharm Des. 2013. PMID: 22973961

3

Enhanced efficacy of AKT and FAK kinase combined inhibition in squamous cell lung carcinomas with stable reduction in PTEN.

Cavazzoni A, La Monica S, Alfieri R, Ravelli A, Van Der Steen N, Sciarrillo R, Madeddu D, Lagrasta CAM, Quaini F, Bonelli M, Fumarola C, Cretella D, Digiacomo G, Tiseo M, Peters GJ, Ardizzoni A, Petronini PG, Giovannetti E. Cavazzoni A, et al. Among authors: sciarrillo r. Oncotarget. 2017 May 23;8(32):53068-53083. doi: 10.18632/oncotarget.18087. eCollection 2017 Aug 8. Oncotarget. 2017. PMID: 28881794 Free PMC article.

4

Synergistic interaction of novel lactate dehydrogenase inhibitors with gemcitabine against pancreatic cancer cells in hypoxia.

Maftouh M, Avan A, Sciarrillo R, Granchi C, Leon LG, Rani R, Funel N, Smid K, Honeywell R, Boggi U, Minutolo F, Peters GJ, Giovannetti E. Maftouh M, et al. Among authors: sciarrillo r. Br J Cancer. 2014 Jan 7;110(1):172-82. doi: 10.1038/bjc.2013.681. Epub 2013 Oct 31. Br J Cancer. 2014. PMID: 24178759 Free PMC article.

5

Splicing modulation as novel therapeutic strategy against diffuse malignant peritoneal mesothelioma.

Sciarrillo R, Wojtuszkiewicz A, El Hassouni B, Funel N, Gandellini P, Lagerweij T, Buonamici S, Blijlevens M, Zeeuw van der Laan EA, Zaffaroni N, Deraco M, Kusamura S, Würdinger T, Peters GJ, Molthoff CFM, Jansen G, Kaspers GJL, Cloos J, Giovannetti E. Sciarrillo R, et al. EBioMedicine. 2019 Jan;39:215-225. doi: 10.1016/j.ebiom.2018.12.025. Epub 2018 Dec 20. EBioMedicine. 2019. PMID: 30581150 Free PMC article.

6

The role of alternative splicing in cancer: From oncogenesis to drug resistance.

Sciarrillo R, Wojtuszkiewicz A, Assaraf YG, Jansen G, Kaspers GJL, Giovannetti E, Cloos J. Sciarrillo R, et al. Drug Resist Updat. 2020 Dec;53:100728. doi: 10.1016/j.drup.2020.100728. Epub 2020 Sep 28. Drug Resist Updat. 2020. PMID: 33070093 Free article. Review.

7

Synergistic activity of the c-Met and tubulin inhibitor tivantinib (ARQ197) with pemetrexed in mesothelioma cells.

Leon LG, Gemelli M, Sciarrillo R, Avan A, Funel N, Giovannetti E. Leon LG, et al. Among authors: sciarrillo r. Curr Drug Targets. 2014;15(14):1331-40. doi: 10.2174/1389450116666141205160924. Curr Drug Targets. 2014. PMID: 25483224

8

Glucocorticoid Resistant Pediatric Acute Lymphoblastic Leukemia Samples Display Altered Splicing Profile and Vulnerability to Spliceosome Modulation.

Sciarrillo R, Wojtuszkiewicz A, Kooi IE, Leon LG, Sonneveld E, Kuiper RP, Jansen G, Giovannetti E, Kaspers GJL, Cloos J. Sciarrillo R, et al. Cancers (Basel). 2020 Mar 19;12(3):723. doi: 10.3390/cancers12030723. Cancers (Basel). 2020. PMID: 32204435 Free PMC article.

9

Silencing Core Spliceosome Sm Gene Expression Induces a Cytotoxic Splicing Switch in the Proteasome Subunit Beta 3 mRNA in Non-Small Cell Lung Cancer Cells.

Blijlevens M, Komor MA, Sciarrillo R, Smit EF, Fijneman RJA, van Beusechem VW. Blijlevens M, et al. Among authors: sciarrillo r. Int J Mol Sci. 2020 Jun 12;21(12):4192. doi: 10.3390/ijms21124192. Int J Mol Sci. 2020. PMID: 32545483 Free PMC article.

10

Using RNA-sequencing to Detect Novel Splice Variants Related to Drug Resistance in In Vitro Cancer Models.

Sciarrillo R, Wojtuszkiewicz A, Kooi IE, Gómez VE, Boggi U, Jansen G, Kaspers GJ, Cloos J, Giovannetti E. Sciarrillo R, et al. J Vis Exp. 2016 Dec 9;(118):54714. doi: 10.3791/54714. J Vis Exp. 2016. PMID: 28060337 Free PMC article.

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