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Population pharmacokinetic/pharmacodynamic models of JNJ-64794964, a toll-like receptor 7 agonist, in healthy adult participants.
Wu LS, Hu Y, Gane EJ, Slaets L, De Creus A, Ding Y, Niu J, Schwabe C, Goeyvaerts N, Xu Z, Huo D, Tuefferd M, Verbrugge I, Van Remoortere P, Schwertschlag U, Vandenbossche J. Wu LS, et al. Among authors: schwertschlag u. Antivir Ther. 2023 Feb;28(1):13596535231151626. doi: 10.1177/13596535231151626. Antivir Ther. 2023. PMID: 36691849 Free article.
Randomized, double blind controlled trial of subcutaneous recombinant human interleukin-11 versus prednisolone in active Crohn's disease.
Herrlinger KR, Witthoeft T, Raedler A, Bokemeyer B, Krummenerl T, Schulzke JD, Boerner N, Kueppers B, Emmrich J, Mescheder A, Schwertschlag U, Shapiro M, Stange EF. Herrlinger KR, et al. Among authors: schwertschlag u. Am J Gastroenterol. 2006 Apr;101(4):793-7. doi: 10.1111/j.1572-0241.2005.00356.x. Am J Gastroenterol. 2006. PMID: 16635225 Clinical Trial.
Molecular classification of Crohn's disease and ulcerative colitis patients using transcriptional profiles in peripheral blood mononuclear cells.
Burczynski ME, Peterson RL, Twine NC, Zuberek KA, Brodeur BJ, Casciotti L, Maganti V, Reddy PS, Strahs A, Immermann F, Spinelli W, Schwertschlag U, Slager AM, Cotreau MM, Dorner AJ. Burczynski ME, et al. Among authors: schwertschlag u. J Mol Diagn. 2006 Feb;8(1):51-61. doi: 10.2353/jmoldx.2006.050079. J Mol Diagn. 2006. PMID: 16436634 Free PMC article.
A single administration of recombinant human interleukin-12 is associated with increased expression levels of interferon-gamma and signal transducer and activator of transcription in healthy subjects.
Trudeau C, Cotreau MM, Stonis L, Dykstra KH, Oestreicher JL, Strahs A, Dorner AJ, Van Cleave VH, Trepicchio WL, Schwertschlag US. Trudeau C, et al. Among authors: schwertschlag us. J Clin Pharmacol. 2005 Jun;45(6):649-58. doi: 10.1177/0091270005276116. J Clin Pharmacol. 2005. PMID: 15901746
Anti-interleukin-12 antibody for active Crohn's disease.
Mannon PJ, Fuss IJ, Mayer L, Elson CO, Sandborn WJ, Present D, Dolin B, Goodman N, Groden C, Hornung RL, Quezado M, Yang Z, Neurath MF, Salfeld J, Veldman GM, Schwertschlag U, Strober W; Anti-IL-12 Crohn's Disease Study Group. Mannon PJ, et al. Among authors: schwertschlag u. N Engl J Med. 2004 Nov 11;351(20):2069-79. doi: 10.1056/NEJMoa033402. N Engl J Med. 2004. PMID: 15537905 Free article. Clinical Trial.
45 results