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Molecular characterization of CNS paragangliomas identifies cauda equina paragangliomas as a distinct tumor entity.
Schweizer L, Thierfelder F, Thomas C, Soschinski P, Suwala A, Stichel D, Wefers AK, Wessels L, Misch M, Kim HY, Jödicke R, Teichmann D, Kaul D, Kahn J, Bockmayr M, Hasselblatt M, Younsi A, Unterberg A, Knie B, Walter J, Al Safatli D, May SA, Jödicke A, Ntoulias G, Moskopp D, Vajkoczy P, Heppner FL, Capper D, Hartmann W, Hartmann C, von Deimling A, Reuss DE, Schöler A, Koch A. Schweizer L, et al. Acta Neuropathol. 2020 Dec;140(6):893-906. doi: 10.1007/s00401-020-02218-7. Epub 2020 Sep 14. Acta Neuropathol. 2020. PMID: 32926213 Free PMC article.
Secretory meningiomas are defined by combined KLF4 K409Q and TRAF7 mutations.
Reuss DE, Piro RM, Jones DT, Simon M, Ketter R, Kool M, Becker A, Sahm F, Pusch S, Meyer J, Hagenlocher C, Schweizer L, Capper D, Kickingereder P, Mucha J, Koelsche C, Jäger N, Santarius T, Tarpey PS, Stephens PJ, Andrew Futreal P, Wellenreuther R, Kraus J, Lenartz D, Herold-Mende C, Hartmann C, Mawrin C, Giese N, Eils R, Collins VP, König R, Wiestler OD, Pfister SM, von Deimling A. Reuss DE, et al. Among authors: schweizer l. Acta Neuropathol. 2013 Mar;125(3):351-8. doi: 10.1007/s00401-013-1093-x. Epub 2013 Feb 12. Acta Neuropathol. 2013. PMID: 23404370
Meningeal hemangiopericytoma and solitary fibrous tumors carry the NAB2-STAT6 fusion and can be diagnosed by nuclear expression of STAT6 protein.
Schweizer L, Koelsche C, Sahm F, Piro RM, Capper D, Reuss DE, Pusch S, Habel A, Meyer J, Göck T, Jones DT, Mawrin C, Schittenhelm J, Becker A, Heim S, Simon M, Herold-Mende C, Mechtersheimer G, Paulus W, König R, Wiestler OD, Pfister SM, von Deimling A. Schweizer L, et al. Acta Neuropathol. 2013 May;125(5):651-8. doi: 10.1007/s00401-013-1117-6. Epub 2013 Apr 11. Acta Neuropathol. 2013. PMID: 23575898
AKT1E17K mutations cluster with meningothelial and transitional meningiomas and can be detected by SFRP1 immunohistochemistry.
Sahm F, Bissel J, Koelsche C, Schweizer L, Capper D, Reuss D, Böhmer K, Lass U, Göck T, Kalis K, Meyer J, Habel A, Brehmer S, Mittelbronn M, Jones DT, Schittenhelm J, Urbschat S, Ketter R, Heim S, Mawrin C, Hainfellner JA, Berghoff AS, Preusser M, Becker A, Herold-Mende C, Unterberg A, Hartmann C, Kickingereder P, Collins VP, Pfister SM, von Deimling A. Sahm F, et al. Among authors: schweizer l. Acta Neuropathol. 2013 Nov;126(5):757-62. doi: 10.1007/s00401-013-1187-5. Epub 2013 Oct 6. Acta Neuropathol. 2013. PMID: 24096618
Nuclear relocation of STAT6 reliably predicts NAB2-STAT6 fusion for the diagnosis of solitary fibrous tumour.
Koelsche C, Schweizer L, Renner M, Warth A, Jones DT, Sahm F, Reuss DE, Capper D, Knösel T, Schulz B, Petersen I, Ulrich A, Renker EK, Lehner B, Pfister SM, Schirmacher P, von Deimling A, Mechtersheimer G. Koelsche C, et al. Among authors: schweizer l. Histopathology. 2014 Nov;65(5):613-22. doi: 10.1111/his.12431. Epub 2014 Sep 2. Histopathology. 2014. PMID: 24702701
Integrated DNA methylation and copy-number profiling identify three clinically and biologically relevant groups of anaplastic glioma.
Wiestler B, Capper D, Sill M, Jones DT, Hovestadt V, Sturm D, Koelsche C, Bertoni A, Schweizer L, Korshunov A, Weiß EK, Schliesser MG, Radbruch A, Herold-Mende C, Roth P, Unterberg A, Hartmann C, Pietsch T, Reifenberger G, Lichter P, Radlwimmer B, Platten M, Pfister SM, von Deimling A, Weller M, Wick W. Wiestler B, et al. Among authors: schweizer l. Acta Neuropathol. 2014 Oct;128(4):561-71. doi: 10.1007/s00401-014-1315-x. Epub 2014 Jul 10. Acta Neuropathol. 2014. PMID: 25008768 Free article.
ATRX and IDH1-R132H immunohistochemistry with subsequent copy number analysis and IDH sequencing as a basis for an "integrated" diagnostic approach for adult astrocytoma, oligodendroglioma and glioblastoma.
Reuss DE, Sahm F, Schrimpf D, Wiestler B, Capper D, Koelsche C, Schweizer L, Korshunov A, Jones DT, Hovestadt V, Mittelbronn M, Schittenhelm J, Herold-Mende C, Unterberg A, Platten M, Weller M, Wick W, Pfister SM, von Deimling A. Reuss DE, et al. Among authors: schweizer l. Acta Neuropathol. 2015 Jan;129(1):133-46. doi: 10.1007/s00401-014-1370-3. Epub 2014 Nov 27. Acta Neuropathol. 2015. PMID: 25427834 Free article.
145 results