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A monoclonal antibody targeting nonjunctional claudin-1 inhibits fibrosis in patient-derived models by modulating cell plasticity.
Roehlen N, Saviano A, El Saghire H, Crouchet E, Nehme Z, Del Zompo F, Jühling F, Oudot MA, Durand SC, Duong FHT, Cherradi S, Gonzalez Motos V, Almeida N, Ponsolles C, Heydmann L, Ostyn T, Lallement A, Pessaux P, Felli E, Cavalli A, Sgrignani J, Thumann C, Koutsopoulos O, Fuchs BC, Hoshida Y, Hofmann M, Vyberg M, Viuff BM, Galsgaard ED, Elson G, Toso A, Meyer M, Iacone R, Schweighoffer T, Teixeira G, Moll S, De Vito C, Roskams T, Davidson I, Heide D, Heikenwälder M, Zeisel MB, Lupberger J, Mailly L, Schuster C, Baumert TF. Roehlen N, et al. Among authors: schweighoffer t. Sci Transl Med. 2022 Dec 21;14(676):eabj4221. doi: 10.1126/scitranslmed.abj4221. Epub 2022 Dec 21. Sci Transl Med. 2022. PMID: 36542691
Treatment of HCC with claudin-1-specific antibodies suppresses carcinogenic signaling and reprograms the tumor microenvironment.
Roehlen N, Muller M, Nehme Z, Crouchet E, Jühling F, Del Zompo F, Cherradi S, Duong FHT, Almeida N, Saviano A, Fernández-Vaquero M, Riedl T, El Saghire H, Durand SC, Ponsolles C, Oudot MA, Martin R, Brignon N, Felli E, Pessaux P, Lallement A, Davidson I, Bandiera S, Thumann C, Marchand P, Moll S, Nicolay B, Bardeesy N, Hoshida Y, Heikenwälder M, Iacone R, Toso A, Meyer M, Elson G, Schweighoffer T, Teixeira G, Zeisel MB, Laquerriere P, Lupberger J, Schuster C, Mailly L, Baumert TF. Roehlen N, et al. Among authors: schweighoffer t. J Hepatol. 2023 Feb;78(2):343-355. doi: 10.1016/j.jhep.2022.10.011. Epub 2022 Oct 27. J Hepatol. 2023. PMID: 36309131 Free article.
Fingerprints of CD8+ T cells on human pre-plasma and memory B cells.
Strittmatter-Keller U, Walter C, Rauld C, Egli N, Regairaz C, Rabe S, Zenke G, Carballido J, Schweighoffer T. Strittmatter-Keller U, et al. Among authors: schweighoffer t. PLoS One. 2018 Dec 12;13(12):e0208187. doi: 10.1371/journal.pone.0208187. eCollection 2018. PLoS One. 2018. PMID: 30540814 Free PMC article.
Human CD180 Transmits Signals via the PIM-1L Kinase.
Egli N, Zajonz A, Burger MT, Schweighoffer T. Egli N, et al. Among authors: schweighoffer t. PLoS One. 2015 Nov 10;10(11):e0142741. doi: 10.1371/journal.pone.0142741. eCollection 2015. PLoS One. 2015. PMID: 26555723 Free PMC article.
SAP-mediated inhibition of diacylglycerol kinase α regulates TCR-induced diacylglycerol signaling.
Baldanzi G, Pighini A, Bettio V, Rainero E, Traini S, Chianale F, Porporato PE, Filigheddu N, Mesturini R, Song S, Schweighoffer T, Patrussi L, Baldari CT, Zhong XP, van Blitterswijk WJ, Sinigaglia F, Nichols KE, Rubio I, Parolini O, Graziani A. Baldanzi G, et al. Among authors: schweighoffer t. J Immunol. 2011 Dec 1;187(11):5941-51. doi: 10.4049/jimmunol.1002476. Epub 2011 Nov 2. J Immunol. 2011. PMID: 22048771 Free PMC article.
EWI-2/CD316 is an inducible receptor of HSPA8 on human dendritic cells.
Kettner S, Kalthoff F, Graf P, Priller E, Kricek F, Lindley I, Schweighoffer T. Kettner S, et al. Among authors: schweighoffer t. Mol Cell Biol. 2007 Nov;27(21):7718-26. doi: 10.1128/MCB.00180-07. Epub 2007 Sep 4. Mol Cell Biol. 2007. PMID: 17785435 Free PMC article.
34 results