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Human pericytes degrade diverse α-synuclein aggregates.
Dieriks BV, Highet B, Alik A, Bellande T, Stevenson TJ, Low V, Park TI, Correia J, Schweder P, Faull RLM, Melki R, Curtis MA, Dragunow M. Dieriks BV, et al. Among authors: schweder p. PLoS One. 2022 Nov 18;17(11):e0277658. doi: 10.1371/journal.pone.0277658. eCollection 2022. PLoS One. 2022. PMID: 36399706 Free PMC article.
Elucidating the cellular uptake mechanisms of heptamethine cyanine dye analogues for their use as an anticancer drug-carrier molecule for the treatment of glioblastoma.
Cooper E, Choi PJ, Hwang K, Nam KM, Kim CY, Shaban T, Schweder P, Mee E, Correia J, Turner C, Faull RLM, Denny WA, Noguchi K, Dragunow M, Jose J, Park TI. Cooper E, et al. Among authors: schweder p. Chem Biol Drug Des. 2023 Mar;101(3):696-716. doi: 10.1111/cbdd.14171. Epub 2022 Nov 29. Chem Biol Drug Des. 2023. PMID: 36323652
Single-cell image analysis reveals over-expression of organic anion transporting polypeptides (OATPs) in human glioblastoma tissue.
Cooper E, Woolf Z, Swanson MEV, Correia J, Schweder P, Mee E, Heppner P, Turner C, Faull RLM, Scotter EL, Denny WA, Choi PJ, Dragunow M, Jose J, Park TI. Cooper E, et al. Among authors: schweder p. Neurooncol Adv. 2022 Oct 14;4(1):vdac166. doi: 10.1093/noajnl/vdac166. eCollection 2022 Jan-Dec. Neurooncol Adv. 2022. PMID: 36382105 Free PMC article.
Involvement of the tumour necrosis factor receptor system in glioblastoma cell death induced by palbociclib-heptamethine cyanine dye conjugate.
Cooper E, Oyagawa CRM, Johnson R, Choi PJ, Foliaki JM, Correia J, Schweder P, Heppner P, Mee E, Turner C, Faull R, Denny WA, Dragunow M, Jose J, Park TI. Cooper E, et al. Among authors: schweder p. Cell Commun Signal. 2024 Jan 11;22(1):30. doi: 10.1186/s12964-023-01277-z. Cell Commun Signal. 2024. PMID: 38212807 Free PMC article.
Pericytes take up and degrade α-synuclein but succumb to apoptosis under cellular stress.
Stevenson TJ, Johnson RH, Savistchenko J, Rustenhoven J, Woolf Z, Smyth LCD, Murray HC, Faull RLM, Correia J, Schweder P, Heppner P, Turner C, Melki R, Dieriks BV, Curtis MA, Dragunow M. Stevenson TJ, et al. Among authors: schweder p. Sci Rep. 2022 Oct 15;12(1):17314. doi: 10.1038/s41598-022-20261-0. Sci Rep. 2022. PMID: 36243723 Free PMC article.
Characterisation of PDGF-BB:PDGFRβ signalling pathways in human brain pericytes: evidence of disruption in Alzheimer's disease.
Smyth LCD, Highet B, Jansson D, Wu J, Rustenhoven J, Aalderink M, Tan A, Li S, Johnson R, Coppieters N, Handley R, Narayan P, Singh-Bains MK, Schweder P, Turner C, Mee EW, Heppner P, Correia J, Park TI, Curtis MA, Faull RLM, Dragunow M. Smyth LCD, et al. Among authors: schweder p. Commun Biol. 2022 Mar 17;5(1):235. doi: 10.1038/s42003-022-03180-8. Commun Biol. 2022. PMID: 35301433 Free PMC article.
Routine culture and study of adult human brain cells from neurosurgical specimens.
Park TI, Smyth LCD, Aalderink M, Woolf ZR, Rustenhoven J, Lee K, Jansson D, Smith A, Feng S, Correia J, Heppner P, Schweder P, Mee E, Dragunow M. Park TI, et al. Among authors: schweder p. Nat Protoc. 2022 Feb;17(2):190-221. doi: 10.1038/s41596-021-00637-8. Epub 2022 Jan 12. Nat Protoc. 2022. PMID: 35022619 Review.
50 results