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A structural model of the iRhom-ADAM17 sheddase complex reveals functional insights into its trafficking and activity.
Kahveci-Türköz S, Bläsius K, Wozniak J, Rinkens C, Seifert A, Kasparek P, Ohm H, Oltzen S, Nieszporek M, Schwarz N, Babendreyer A, Preisinger C, Sedlacek R, Ludwig A, Düsterhöft S. Kahveci-Türköz S, et al. Among authors: schwarz n. Cell Mol Life Sci. 2023 Apr 29;80(5):135. doi: 10.1007/s00018-023-04783-y. Cell Mol Life Sci. 2023. PMID: 37119365 Free PMC article.
Requirements for leukocyte transmigration via the transmembrane chemokine CX3CL1.
Schwarz N, Pruessmeyer J, Hess FM, Dreymueller D, Pantaler E, Koelsch A, Windoffer R, Voss M, Sarabi A, Weber C, Sechi AS, Uhlig S, Ludwig A. Schwarz N, et al. Cell Mol Life Sci. 2010 Dec;67(24):4233-48. doi: 10.1007/s00018-010-0433-4. Epub 2010 Jun 18. Cell Mol Life Sci. 2010. PMID: 20559678
Leukocytes require ADAM10 but not ADAM17 for their migration and inflammatory recruitment into the alveolar space.
Pruessmeyer J, Hess FM, Alert H, Groth E, Pasqualon T, Schwarz N, Nyamoya S, Kollert J, van der Vorst E, Donners M, Martin C, Uhlig S, Saftig P, Dreymueller D, Ludwig A. Pruessmeyer J, et al. Among authors: schwarz n. Blood. 2014 Jun 26;123(26):4077-88. doi: 10.1182/blood-2013-09-511543. Epub 2014 May 15. Blood. 2014. PMID: 24833351 Free article.
A transmembrane C-terminal fragment of syndecan-1 is generated by the metalloproteinase ADAM17 and promotes lung epithelial tumor cell migration and lung metastasis formation.
Pasqualon T, Pruessmeyer J, Weidenfeld S, Babendreyer A, Groth E, Schumacher J, Schwarz N, Denecke B, Jahr H, Zimmermann P, Dreymueller D, Ludwig A. Pasqualon T, et al. Among authors: schwarz n. Cell Mol Life Sci. 2015 Oct;72(19):3783-801. doi: 10.1007/s00018-015-1912-4. Epub 2015 Apr 26. Cell Mol Life Sci. 2015. PMID: 25912030
A cytoplasmic C-terminal fragment of Syndecan-1 is generated by sequential proteolysis and antagonizes Syndecan-1 dependent lung tumor cell migration.
Pasqualon T, Pruessmeyer J, Jankowski V, Babendreyer A, Groth E, Schumacher J, Koenen A, Weidenfeld S, Schwarz N, Denecke B, Jahr H, Dreymueller D, Jankowski J, Ludwig A. Pasqualon T, et al. Among authors: schwarz n. Oncotarget. 2015 Oct 13;6(31):31295-312. doi: 10.18632/oncotarget.5174. Oncotarget. 2015. PMID: 26378057 Free PMC article.
The DRF motif of CXCR6 as chemokine receptor adaptation to adhesion.
Koenen A, Babendreyer A, Schumacher J, Pasqualon T, Schwarz N, Seifert A, Deupi X, Ludwig A, Dreymueller D. Koenen A, et al. Among authors: schwarz n. PLoS One. 2017 Mar 7;12(3):e0173486. doi: 10.1371/journal.pone.0173486. eCollection 2017. PLoS One. 2017. PMID: 28267793 Free PMC article.
504 results