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Page 1
TGF-β signaling mediates endothelial-to-mesenchymal transition (EndMT) during vein graft remodeling.
Cooley BC, Nevado J, Mellad J, Yang D, St Hilaire C, Negro A, Fang F, Chen G, San H, Walts AD, Schwartzbeck RL, Taylor B, Lanzer JD, Wragg A, Elagha A, Beltran LE, Berry C, Feil R, Virmani R, Ladich E, Kovacic JC, Boehm M. Cooley BC, et al. Among authors: schwartzbeck rl. Sci Transl Med. 2014 Mar 12;6(227):227ra34. doi: 10.1126/scitranslmed.3006927. Sci Transl Med. 2014. PMID: 24622514 Free PMC article.
Increased activity of TNAP compensates for reduced adenosine production and promotes ectopic calcification in the genetic disease ACDC.
Jin H, St Hilaire C, Huang Y, Yang D, Dmitrieva NI, Negro A, Schwartzbeck R, Liu Y, Yu Z, Walts A, Davaine JM, Lee DY, Donahue D, Hsu KS, Chen J, Cheng T, Gahl W, Chen G, Boehm M. Jin H, et al. Among authors: schwartzbeck r. Sci Signal. 2016 Dec 13;9(458):ra121. doi: 10.1126/scisignal.aaf9109. Sci Signal. 2016. PMID: 27965423 Free PMC article.
Generation of human induced pluripotent stem cell lines (NIHTVBi011-A, NIHTVBi012-A, NIHTVBi013-A) from autosomal dominant Hyper IgE syndrome (AD-HIES) patients carrying STAT3 mutation.
Jin H, Yu Z, Navarengom K, Liu Y, Dmitrieva N, Hsu AP, Schwartzbeck R, Cudrici C, Ferrante EA, Yang D, Holland SM, Freeman AF, Boehm M, Chen G. Jin H, et al. Among authors: schwartzbeck r. Stem Cell Res. 2019 Dec;41:101586. doi: 10.1016/j.scr.2019.101586. Epub 2019 Oct 17. Stem Cell Res. 2019. PMID: 31707214 Free PMC article.
Generation of human induced pluripotent stem cells (NIHTVBi004-A, NIHTVBi005-A, NIHTVBi006-A, NIHTVBi007-A, NIHTVBi008-A) from 5 CADASIL patients with NOTCH3 mutation.
Chen G, Li Z, Liu Y, Chen D, Beers J, Cudrici C, Ferrante EA, Schwartzbeck R, Dmitrieva N, Yang D, Zou J, Iruela-Arispe ML, Boehm M. Chen G, et al. Among authors: schwartzbeck r. Stem Cell Res. 2020 May;45:101821. doi: 10.1016/j.scr.2020.101821. Epub 2020 Apr 22. Stem Cell Res. 2020. PMID: 32344328 Free PMC article.
Impaired angiogenesis and extracellular matrix metabolism in autosomal-dominant hyper-IgE syndrome.
Dmitrieva NI, Walts AD, Nguyen DP, Grubb A, Zhang X, Wang X, Ping X, Jin H, Yu Z, Yu ZX, Yang D, Schwartzbeck R, Dalgard CL, Kozel BA, Levin MD, Knutsen RH, Liu D, Milner JD, López DB, O'Connell MP, Lee CR, Myles IA, Hsu AP, Freeman AF, Holland SM, Chen G, Boehm M. Dmitrieva NI, et al. Among authors: schwartzbeck r. J Clin Invest. 2020 Aug 3;130(8):4167-4181. doi: 10.1172/JCI135490. J Clin Invest. 2020. PMID: 32369445 Free PMC article. Clinical Trial.