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Obesity is associated with hypothalamic injury in rodents and humans.
Thaler JP, Yi CX, Schur EA, Guyenet SJ, Hwang BH, Dietrich MO, Zhao X, Sarruf DA, Izgur V, Maravilla KR, Nguyen HT, Fischer JD, Matsen ME, Wisse BE, Morton GJ, Horvath TL, Baskin DG, Tschöp MH, Schwartz MW. Thaler JP, et al. Among authors: schwartz mw. J Clin Invest. 2012 Jan;122(1):153-62. doi: 10.1172/JCI59660. Epub 2011 Dec 27. J Clin Invest. 2012. PMID: 22201683 Free PMC article.
Inhibition of hypothalamic neuropeptide Y gene expression by insulin.
Schwartz MW, Sipols AJ, Marks JL, Sanacora G, White JD, Scheurink A, Kahn SE, Baskin DG, Woods SC, Figlewicz DP, et al. Schwartz MW, et al. Endocrinology. 1992 Jun;130(6):3608-16. doi: 10.1210/endo.130.6.1597158. Endocrinology. 1992. PMID: 1597158
Insulin receptor substrate-1 (IRS-1) expression in rat brain.
Baskin DG, Schwartz MW, Sipols AJ, D'Alessio DA, Goldstein BJ, White MF. Baskin DG, et al. Among authors: schwartz mw. Endocrinology. 1994 Apr;134(4):1952-5. doi: 10.1210/endo.134.4.7511094. Endocrinology. 1994. PMID: 7511094
366 results