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Single-cell sequencing of human midbrain reveals glial activation and a Parkinson-specific neuronal state.
Smajić S, Prada-Medina CA, Landoulsi Z, Ghelfi J, Delcambre S, Dietrich C, Jarazo J, Henck J, Balachandran S, Pachchek S, Morris CM, Antony P, Timmermann B, Sauer S, Pereira SL, Schwamborn JC, May P, Grünewald A, Spielmann M. Smajić S, et al. Among authors: schwamborn jc. Brain. 2022 Apr 29;145(3):964-978. doi: 10.1093/brain/awab446. Brain. 2022. PMID: 34919646 Free PMC article.
Derivation of Human Midbrain-Specific Organoids from Neuroepithelial Stem Cells.
Monzel AS, Smits LM, Hemmer K, Hachi S, Moreno EL, van Wuellen T, Jarazo J, Walter J, Brüggemann I, Boussaad I, Berger E, Fleming RMT, Bolognin S, Schwamborn JC. Monzel AS, et al. Among authors: schwamborn jc. Stem Cell Reports. 2017 May 9;8(5):1144-1154. doi: 10.1016/j.stemcr.2017.03.010. Epub 2017 Apr 13. Stem Cell Reports. 2017. PMID: 28416282 Free PMC article.
FACS-Assisted CRISPR-Cas9 Genome Editing Facilitates Parkinson's Disease Modeling.
Arias-Fuenzalida J, Jarazo J, Qing X, Walter J, Gomez-Giro G, Nickels SL, Zaehres H, Schöler HR, Schwamborn JC. Arias-Fuenzalida J, et al. Among authors: schwamborn jc. Stem Cell Reports. 2017 Nov 14;9(5):1423-1431. doi: 10.1016/j.stemcr.2017.08.026. Epub 2017 Oct 5. Stem Cell Reports. 2017. PMID: 28988985 Free PMC article.
3D Cultures of Parkinson's Disease-Specific Dopaminergic Neurons for High Content Phenotyping and Drug Testing.
Bolognin S, Fossépré M, Qing X, Jarazo J, Ščančar J, Moreno EL, Nickels SL, Wasner K, Ouzren N, Walter J, Grünewald A, Glaab E, Salamanca L, Fleming RMT, Antony PMA, Schwamborn JC. Bolognin S, et al. Among authors: schwamborn jc. Adv Sci (Weinh). 2018 Nov 20;6(1):1800927. doi: 10.1002/advs.201800927. eCollection 2019 Jan 9. Adv Sci (Weinh). 2018. PMID: 30643711 Free PMC article.
Automated microfluidic cell culture of stem cell derived dopaminergic neurons.
Kane KIW, Moreno EL, Hachi S, Walter M, Jarazo J, Oliveira MAP, Hankemeier T, Vulto P, Schwamborn JC, Thoma M, Fleming RMT. Kane KIW, et al. Among authors: schwamborn jc. Sci Rep. 2019 Feb 11;9(1):1796. doi: 10.1038/s41598-018-34828-3. Sci Rep. 2019. PMID: 30741972 Free PMC article.
Modeling Parkinson's disease in midbrain-like organoids.
Smits LM, Reinhardt L, Reinhardt P, Glatza M, Monzel AS, Stanslowsky N, Rosato-Siri MD, Zanon A, Antony PM, Bellmann J, Nicklas SM, Hemmer K, Qing X, Berger E, Kalmbach N, Ehrlich M, Bolognin S, Hicks AA, Wegner F, Sterneckert JL, Schwamborn JC. Smits LM, et al. Among authors: schwamborn jc. NPJ Parkinsons Dis. 2019 Apr 5;5:5. doi: 10.1038/s41531-019-0078-4. eCollection 2019. NPJ Parkinsons Dis. 2019. PMID: 30963107 Free PMC article.
Neural Stem Cells of Parkinson's Disease Patients Exhibit Aberrant Mitochondrial Morphology and Functionality.
Walter J, Bolognin S, Antony PMA, Nickels SL, Poovathingal SK, Salamanca L, Magni S, Perfeito R, Hoel F, Qing X, Jarazo J, Arias-Fuenzalida J, Ignac T, Monzel AS, Gonzalez-Cano L, Pereira de Almeida L, Skupin A, Tronstad KJ, Schwamborn JC. Walter J, et al. Among authors: schwamborn jc. Stem Cell Reports. 2019 May 14;12(5):878-889. doi: 10.1016/j.stemcr.2019.03.004. Epub 2019 Apr 11. Stem Cell Reports. 2019. PMID: 30982740 Free PMC article.
124 results