Schwabe JWR - Search Results

1

Aster-dependent nonvesicular transport facilitates dietary cholesterol uptake.

Ferrari A, Whang E, Xiao X, Kennelly JP, Romartinez-Alonso B, Mack JJ, Weston T, Chen K, Kim Y, Tol MJ, Bideyan L, Nguyen A, Gao Y, Cui L, Bedard AH, Sandhu J, Lee SD, Fairall L, Williams KJ, Song W, Munguia P, Russell RA, Martin MG, Jung ME, Jiang H, Schwabe JWR, Young SG, Tontonoz P. Ferrari A, et al. Among authors: schwabe jwr. Science. 2023 Nov 10;382(6671):eadf0966. doi: 10.1126/science.adf0966. Epub 2023 Nov 10. Science. 2023. PMID: 37943936 Free PMC article.

2

Selective Aster inhibitors distinguish vesicular and nonvesicular sterol transport mechanisms.

Xiao X, Kim Y, Romartinez-Alonso B, Sirvydis K, Ory DS, Schwabe JWR, Jung ME, Tontonoz P. Xiao X, et al. Among authors: schwabe jwr. Proc Natl Acad Sci U S A. 2021 Jan 12;118(2):e2024149118. doi: 10.1073/pnas.2024149118. Proc Natl Acad Sci U S A. 2021. PMID: 33376205 Free PMC article.

3

Aster Proteins Facilitate Nonvesicular Plasma Membrane to ER Cholesterol Transport in Mammalian Cells.

Sandhu J, Li S, Fairall L, Pfisterer SG, Gurnett JE, Xiao X, Weston TA, Vashi D, Ferrari A, Orozco JL, Hartman CL, Strugatsky D, Lee SD, He C, Hong C, Jiang H, Bentolila LA, Gatta AT, Levine TP, Ferng A, Lee R, Ford DA, Young SG, Ikonen E, Schwabe JWR, Tontonoz P. Sandhu J, et al. Among authors: schwabe jwr. Cell. 2018 Oct 4;175(2):514-529.e20. doi: 10.1016/j.cell.2018.08.033. Epub 2018 Sep 13. Cell. 2018. PMID: 30220461 Free PMC article.

4

The IDOL-UBE2D complex mediates sterol-dependent degradation of the LDL receptor.

Zhang L, Fairall L, Goult BT, Calkin AC, Hong C, Millard CJ, Tontonoz P, Schwabe JW. Zhang L, et al. Genes Dev. 2011 Jun 15;25(12):1262-74. doi: 10.1101/gad.2056211. Genes Dev. 2011. PMID: 21685362 Free PMC article.

5

Nuclear hormone receptor co-repressors: structure and function.

Watson PJ, Fairall L, Schwabe JW. Watson PJ, et al. Mol Cell Endocrinol. 2012 Jan 30;348(2):440-9. doi: 10.1016/j.mce.2011.08.033. Epub 2011 Sep 8. Mol Cell Endocrinol. 2012. PMID: 21925568 Free PMC article. Review.

6

FERM-dependent E3 ligase recognition is a conserved mechanism for targeted degradation of lipoprotein receptors.

Calkin AC, Goult BT, Zhang L, Fairall L, Hong C, Schwabe JW, Tontonoz P. Calkin AC, et al. Proc Natl Acad Sci U S A. 2011 Dec 13;108(50):20107-12. doi: 10.1073/pnas.1111589108. Epub 2011 Nov 22. Proc Natl Acad Sci U S A. 2011. PMID: 22109552 Free PMC article.

7

Towards an understanding of the structure and function of MTA1.

Millard CJ, Fairall L, Schwabe JW. Millard CJ, et al. Cancer Metastasis Rev. 2014 Dec;33(4):857-67. doi: 10.1007/s10555-014-9513-5. Cancer Metastasis Rev. 2014. PMID: 25352341 Free PMC article. Review.

8

Expression and Purification of Protein Complexes Suitable for Structural Studies Using Mammalian HEK 293F Cells.

Nigi I, Fairall L, Schwabe JWR. Nigi I, et al. Among authors: schwabe jwr. Curr Protoc Protein Sci. 2017 Nov 1;90:5.28.1-5.28.16. doi: 10.1002/cpps.44. Curr Protoc Protein Sci. 2017. PMID: 29091272

9

Structure of HDAC3 bound to co-repressor and inositol tetraphosphate.

Watson PJ, Fairall L, Santos GM, Schwabe JW. Watson PJ, et al. Nature. 2012 Jan 9;481(7381):335-40. doi: 10.1038/nature10728. Nature. 2012. PMID: 22230954 Free PMC article.

10

An evolving understanding of nuclear receptor coregulator proteins.

Millard CJ, Watson PJ, Fairall L, Schwabe JW. Millard CJ, et al. J Mol Endocrinol. 2013 Nov 7;51(3):T23-36. doi: 10.1530/JME-13-0227. Print 2013 Dec. J Mol Endocrinol. 2013. PMID: 24203923 Free PMC article. Review.

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