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Expert opinion on the identification, risk assessment, and mitigation of microorganisms and parasites relevant to xenotransplantation products from pigs.
Groenendaal H, Costard S, Ballard R, Bienhoff S, Challen DC, Dominguez BJ, Kern DR, Miller D, Noordergraaf J, Rudenko L, Schuurman HJ, Spizzo T, Sturos M, Zollers B, Fishman JA. Groenendaal H, et al. Among authors: schuurman hj. Xenotransplantation. 2023 Sep-Oct;30(5):e12815. doi: 10.1111/xen.12815. Epub 2023 Aug 24. Xenotransplantation. 2023. PMID: 37616183
Clinically available immunosuppression averts rejection but not systemic inflammation after porcine islet xenotransplant in cynomolgus macaques.
Graham ML, Ramachandran S, Singh A, Moore MEG, Flanagan EB, Azimzadeh A, Burlak C, Mueller KR, Martins K, Anazawa T, Appakalai BN, Bansal-Pakala P, Murtaugh MP, O'Brien TD, Papas KK, Spizzo T, Schuurman HJ, Hancock WW, Hering BJ. Graham ML, et al. Among authors: schuurman hj. Am J Transplant. 2022 Mar;22(3):745-760. doi: 10.1111/ajt.16876. Epub 2021 Dec 1. Am J Transplant. 2022. PMID: 34704345 Free PMC article.
Histopathology of pig kidney grafts with/without expression of the carbohydrate Neu5Gc in immunosuppressed baboons.
Foote JB, Jagdale A, Yamamoto T, Hara H, Bikhet MH, Schuurman HJ, Nguyen HQ, Ezzelarab M, Ayares D, Anderson DJ, Fatima H, Eckhoff DE, Cooper DKC, Iwase H. Foote JB, et al. Among authors: schuurman hj. Xenotransplantation. 2021 Nov;28(6):e12715. doi: 10.1111/xen.12715. Epub 2021 Oct 13. Xenotransplantation. 2021. PMID: 34644438 Free PMC article.
Evidence suggesting that deletion of expression of N-glycolylneuraminic acid (Neu5Gc) in the organ-source pig is associated with increased antibody-mediated rejection of kidney transplants in baboons.
Iwase H, Jagdale A, Yamamoto T, Bikhet MH, Nguyen HQ, Ezzelarab M, Ayares D, Anderson DJ, Eckhoff DE, Foote JB, Fatima H, Schuurman HJ, Hara H, Cooper DKC. Iwase H, et al. Among authors: schuurman hj. Xenotransplantation. 2021 Jul;28(4):e12700. doi: 10.1111/xen.12700. Epub 2021 May 25. Xenotransplantation. 2021. PMID: 34036638
The final obstacle to successful pre-clinical xenotransplantation?
Yamamoto T, Hara H, Iwase H, Jagdale A, Bikhet MH, Morsi MA, Cui Y, Nguyen HQ, Wang ZY, Anderson DJ, Foote J, Schuurman HJ, Ayares D, Eckhoff DE, Cooper DKC. Yamamoto T, et al. Among authors: schuurman hj. Xenotransplantation. 2020 Sep;27(5):e12596. doi: 10.1111/xen.12596. Epub 2020 Jun 25. Xenotransplantation. 2020. PMID: 32585053
351 results