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The glucose-sensing transcription factor ChREBP is targeted by proline hydroxylation.
Heidenreich S, Weber P, Stephanowitz H, Petricek KM, Schütte T, Oster M, Salo AM, Knauer M, Goehring I, Yang N, Witte N, Schumann A, Sommerfeld M, Muenzner M, Myllyharju J, Krause E, Schupp M. Heidenreich S, et al. Among authors: schupp m. J Biol Chem. 2020 Dec 11;295(50):17158-17168. doi: 10.1074/jbc.RA120.014402. Epub 2020 Oct 6. J Biol Chem. 2020. PMID: 33023907 Free PMC article.
Histone deacetylase 6 (HDAC6) is an essential modifier of glucocorticoid-induced hepatic gluconeogenesis.
Winkler R, Benz V, Clemenz M, Bloch M, Foryst-Ludwig A, Wardat S, Witte N, Trappiel M, Namsolleck P, Mai K, Spranger J, Matthias G, Roloff T, Truee O, Kappert K, Schupp M, Matthias P, Kintscher U. Winkler R, et al. Among authors: schupp m. Diabetes. 2012 Feb;61(2):513-23. doi: 10.2337/db11-0313. Epub 2011 Dec 30. Diabetes. 2012. PMID: 22210316 Free PMC article.
Liver p53 is stabilized upon starvation and required for amino acid catabolism and gluconeogenesis.
Prokesch A, Graef FA, Madl T, Kahlhofer J, Heidenreich S, Schumann A, Moyschewitz E, Pristoynik P, Blaschitz A, Knauer M, Muenzner M, Bogner-Strauss JG, Dohr G, Schulz TJ, Schupp M. Prokesch A, et al. Among authors: schupp m. FASEB J. 2017 Feb;31(2):732-742. doi: 10.1096/fj.201600845R. Epub 2016 Nov 3. FASEB J. 2017. PMID: 27811061 Free PMC article.
., Schumann, A., Moyschewitz, E., Pristoynik, P., Blaschitz, A., Knauer, M., Muenzner, M., Bogner-Strauss, J. G., Dohr, G., Schulz, T. J., Schupp, M. ...
., Schumann, A., Moyschewitz, E., Pristoynik, P., Blaschitz, A., Knauer, M., Muenzner, M., Bogner-Strauss, J. G., Dohr, G., Sc …
Reciprocal regulation of carbon monoxide metabolism and the circadian clock.
Klemz R, Reischl S, Wallach T, Witte N, Jürchott K, Klemz S, Lang V, Lorenzen S, Knauer M, Heidenreich S, Xu M, Ripperger JA, Schupp M, Stanewsky R, Kramer A. Klemz R, et al. Among authors: schupp m. Nat Struct Mol Biol. 2017 Jan;24(1):15-22. doi: 10.1038/nsmb.3331. Epub 2016 Nov 28. Nat Struct Mol Biol. 2017. PMID: 27892932
Retinol saturase coordinates liver metabolism by regulating ChREBP activity.
Heidenreich S, Witte N, Weber P, Goehring I, Tolkachov A, von Loeffelholz C, Döcke S, Bauer M, Stockmann M, Pfeiffer AFH, Birkenfeld AL, Pietzke M, Kempa S, Muenzner M, Schupp M. Heidenreich S, et al. Among authors: schupp m. Nat Commun. 2017 Aug 30;8(1):384. doi: 10.1038/s41467-017-00430-w. Nat Commun. 2017. PMID: 28855500 Free PMC article.
98 results