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Genetic influence on bloodstream infections and sepsis.
Kumpf O, Schumann RR. Kumpf O, et al. Among authors: schumann rr. Int J Antimicrob Agents. 2008 Nov;32 Suppl 1:S44-50. doi: 10.1016/j.ijantimicag.2008.08.002. Epub 2008 Oct 11. Int J Antimicrob Agents. 2008. PMID: 18849152 Review.
TLR4 polymorphisms, infectious diseases, and evolutionary pressure during migration of modern humans.
Ferwerda B, McCall MB, Alonso S, Giamarellos-Bourboulis EJ, Mouktaroudi M, Izagirre N, Syafruddin D, Kibiki G, Cristea T, Hijmans A, Hamann L, Israel S, ElGhazali G, Troye-Blomberg M, Kumpf O, Maiga B, Dolo A, Doumbo O, Hermsen CC, Stalenhoef AF, van Crevel R, Brunner HG, Oh DY, Schumann RR, de la Rúa C, Sauerwein R, Kullberg BJ, van der Ven AJ, van der Meer JW, Netea MG. Ferwerda B, et al. Among authors: schumann rr. Proc Natl Acad Sci U S A. 2007 Oct 16;104(42):16645-50. doi: 10.1073/pnas.0704828104. Epub 2007 Oct 9. Proc Natl Acad Sci U S A. 2007. PMID: 17925445 Free PMC article.
Functional and genetic evidence that the Mal/TIRAP allele variant 180L has been selected by providing protection against septic shock.
Ferwerda B, Alonso S, Banahan K, McCall MB, Giamarellos-Bourboulis EJ, Ramakers BP, Mouktaroudi M, Fain PR, Izagirre N, Syafruddin D, Cristea T, Mockenhaupt FP, Troye-Blomberg M, Kumpf O, Maiga B, Dolo A, Doumbo O, Sundaresan S, Bedu-Addo G, van Crevel R, Hamann L, Oh DY, Schumann RR, Joosten LA, de la Rúa C, Sauerwein R, Drenth JP, Kullberg BJ, van der Ven AJ, Hill AV, Pickkers P, van der Meer JW, O'Neill LA, Netea MG. Ferwerda B, et al. Among authors: schumann rr. Proc Natl Acad Sci U S A. 2009 Jun 23;106(25):10272-7. doi: 10.1073/pnas.0811273106. Epub 2009 Jun 9. Proc Natl Acad Sci U S A. 2009. PMID: 19509334 Free PMC article.
Influence of genetic variations in TLR4 and TIRAP/Mal on the course of sepsis and pneumonia and cytokine release: an observational study in three cohorts.
Kumpf O, Giamarellos-Bourboulis EJ, Koch A, Hamann L, Mouktaroudi M, Oh DY, Latz E, Lorenz E, Schwartz DA, Ferwerda B, Routsi C, Skalioti C, Kullberg BJ, van der Meer JW, Schlag PM, Netea MG, Zacharowski K, Schumann RR. Kumpf O, et al. Among authors: schumann rr. Crit Care. 2010;14(3):R103. doi: 10.1186/cc9047. Epub 2010 Jun 3. Crit Care. 2010. PMID: 20525286 Free PMC article.
The crystal structure of lipopolysaccharide binding protein reveals the location of a frequent mutation that impairs innate immunity.
Eckert JK, Kim YJ, Kim JI, Gürtler K, Oh DY, Sur S, Lundvall L, Hamann L, van der Ploeg A, Pickkers P, Giamarellos-Bourboulis E, Kubarenko AV, Weber AN, Kabesch M, Kumpf O, An HJ, Lee JO, Schumann RR. Eckert JK, et al. Among authors: schumann rr. Immunity. 2013 Oct 17;39(4):647-60. doi: 10.1016/j.immuni.2013.09.005. Epub 2013 Oct 10. Immunity. 2013. PMID: 24120359 Free article.
164 results