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Lipoteichoic acid (LTA) of Streptococcus pneumoniae and Staphylococcus aureus activates immune cells via Toll-like receptor (TLR)-2, lipopolysaccharide-binding protein (LBP), and CD14, whereas TLR-4 and MD-2 are not involved.
Schröder NW, Morath S, Alexander C, Hamann L, Hartung T, Zähringer U, Göbel UB, Weber JR, Schumann RR. Schröder NW, et al. Among authors: schumann rr. J Biol Chem. 2003 May 2;278(18):15587-94. doi: 10.1074/jbc.M212829200. Epub 2003 Feb 19. J Biol Chem. 2003. PMID: 12594207 Free article.
Toll-like receptor (TLR) polymorphisms in African children: Common TLR-4 variants predispose to severe malaria.
Mockenhaupt FP, Cramer JP, Hamann L, Stegemann MS, Eckert J, Oh NR, Otchwemah RN, Dietz E, Ehrhardt S, Schröder NW, Bienzle U, Schumann RR. Mockenhaupt FP, et al. Among authors: schumann rr. Proc Natl Acad Sci U S A. 2006 Jan 3;103(1):177-82. doi: 10.1073/pnas.0506803102. Epub 2005 Dec 21. Proc Natl Acad Sci U S A. 2006. PMID: 16371473 Free PMC article.
164 results