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Antigen Identification for Orphan T Cell Receptors Expressed on Tumor-Infiltrating Lymphocytes.
Gee MH, Han A, Lofgren SM, Beausang JF, Mendoza JL, Birnbaum ME, Bethune MT, Fischer S, Yang X, Gomez-Eerland R, Bingham DB, Sibener LV, Fernandes RA, Velasco A, Baltimore D, Schumacher TN, Khatri P, Quake SR, Davis MM, Garcia KC. Gee MH, et al. Among authors: schumacher tn. Cell. 2018 Jan 25;172(3):549-563.e16. doi: 10.1016/j.cell.2017.11.043. Epub 2017 Dec 21. Cell. 2018. PMID: 29275860 Free PMC article.
Gene transfer of MHC-restricted receptors.
Kessels HW, Wolkers MC, Schumacher TN. Kessels HW, et al. Among authors: schumacher tn. Methods Mol Med. 2005;109:201-14. doi: 10.1385/1-59259-862-5:201. Methods Mol Med. 2005. PMID: 15585923
Selecting highly affine and well-expressed TCRs for gene therapy of melanoma.
Jorritsma A, Gomez-Eerland R, Dokter M, van de Kasteele W, Zoet YM, Doxiadis II, Rufer N, Romero P, Morgan RA, Schumacher TN, Haanen JB. Jorritsma A, et al. Among authors: schumacher tn. Blood. 2007 Nov 15;110(10):3564-72. doi: 10.1182/blood-2007-02-075010. Epub 2007 Jul 27. Blood. 2007. PMID: 17660381 Free article.
Evidence for a TCR affinity threshold delimiting maximal CD8 T cell function.
Schmid DA, Irving MB, Posevitz V, Hebeisen M, Posevitz-Fejfar A, Sarria JC, Gomez-Eerland R, Thome M, Schumacher TN, Romero P, Speiser DE, Zoete V, Michielin O, Rufer N. Schmid DA, et al. Among authors: schumacher tn. J Immunol. 2010 May 1;184(9):4936-46. doi: 10.4049/jimmunol.1000173. Epub 2010 Mar 29. J Immunol. 2010. PMID: 20351194
Tissue-resident memory CD8+ T cells continuously patrol skin epithelia to quickly recognize local antigen.
Ariotti S, Beltman JB, Chodaczek G, Hoekstra ME, van Beek AE, Gomez-Eerland R, Ritsma L, van Rheenen J, Marée AF, Zal T, de Boer RJ, Haanen JB, Schumacher TN. Ariotti S, et al. Among authors: schumacher tn. Proc Natl Acad Sci U S A. 2012 Nov 27;109(48):19739-44. doi: 10.1073/pnas.1208927109. Epub 2012 Nov 12. Proc Natl Acad Sci U S A. 2012. PMID: 23150545 Free PMC article.
High-throughput identification of antigen-specific TCRs by TCR gene capture.
Linnemann C, Heemskerk B, Kvistborg P, Kluin RJ, Bolotin DA, Chen X, Bresser K, Nieuwland M, Schotte R, Michels S, Gomez-Eerland R, Jahn L, Hombrink P, Legrand N, Shu CJ, Mamedov IZ, Velds A, Blank CU, Haanen JB, Turchaninova MA, Kerkhoven RM, Spits H, Hadrup SR, Heemskerk MH, Blankenstein T, Chudakov DM, Bendle GM, Schumacher TN. Linnemann C, et al. Among authors: schumacher tn. Nat Med. 2013 Nov;19(11):1534-41. doi: 10.1038/nm.3359. Epub 2013 Oct 13. Nat Med. 2013. PMID: 24121928
Manufacture of gene-modified human T-cells with a memory stem/central memory phenotype.
Gomez-Eerland R, Nuijen B, Heemskerk B, van Rooij N, van den Berg JH, Beijnen JH, Uckert W, Kvistborg P, Schumacher TN, Haanen JB, Jorritsma A. Gomez-Eerland R, et al. Among authors: schumacher tn. Hum Gene Ther Methods. 2014 Oct;25(5):277-87. doi: 10.1089/hgtb.2014.004. Epub 2014 Sep 22. Hum Gene Ther Methods. 2014. PMID: 25143008 Free PMC article.
313 results