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Page 1
Antigen receptor repertoire profiling from RNA-seq data.
Bolotin DA, Poslavsky S, Davydov AN, Frenkel FE, Fanchi L, Zolotareva OI, Hemmers S, Putintseva EV, Obraztsova AS, Shugay M, Ataullakhanov RI, Rudensky AY, Schumacher TN, Chudakov DM. Bolotin DA, et al. Among authors: schumacher tn. Nat Biotechnol. 2017 Oct 11;35(10):908-911. doi: 10.1038/nbt.3979. Nat Biotechnol. 2017. PMID: 29020005 Free PMC article. No abstract available.
Pairing of T-cell receptor chains via emulsion PCR.
Turchaninova MA, Britanova OV, Bolotin DA, Shugay M, Putintseva EV, Staroverov DB, Sharonov G, Shcherbo D, Zvyagin IV, Mamedov IZ, Linnemann C, Schumacher TN, Chudakov DM. Turchaninova MA, et al. Among authors: schumacher tn. Eur J Immunol. 2013 Sep;43(9):2507-15. doi: 10.1002/eji.201343453. Epub 2013 Jun 26. Eur J Immunol. 2013. PMID: 23696157 Free article.
High-throughput identification of antigen-specific TCRs by TCR gene capture.
Linnemann C, Heemskerk B, Kvistborg P, Kluin RJ, Bolotin DA, Chen X, Bresser K, Nieuwland M, Schotte R, Michels S, Gomez-Eerland R, Jahn L, Hombrink P, Legrand N, Shu CJ, Mamedov IZ, Velds A, Blank CU, Haanen JB, Turchaninova MA, Kerkhoven RM, Spits H, Hadrup SR, Heemskerk MH, Blankenstein T, Chudakov DM, Bendle GM, Schumacher TN. Linnemann C, et al. Among authors: schumacher tn. Nat Med. 2013 Nov;19(11):1534-41. doi: 10.1038/nm.3359. Epub 2013 Oct 13. Nat Med. 2013. PMID: 24121928
Towards error-free profiling of immune repertoires.
Shugay M, Britanova OV, Merzlyak EM, Turchaninova MA, Mamedov IZ, Tuganbaev TR, Bolotin DA, Staroverov DB, Putintseva EV, Plevova K, Linnemann C, Shagin D, Pospisilova S, Lukyanov S, Schumacher TN, Chudakov DM. Shugay M, et al. Among authors: schumacher tn. Nat Methods. 2014 Jun;11(6):653-5. doi: 10.1038/nmeth.2960. Epub 2014 May 4. Nat Methods. 2014. PMID: 24793455
Neoadjuvant versus adjuvant ipilimumab plus nivolumab in macroscopic stage III melanoma.
Blank CU, Rozeman EA, Fanchi LF, Sikorska K, van de Wiel B, Kvistborg P, Krijgsman O, van den Braber M, Philips D, Broeks A, van Thienen JV, Mallo HA, Adriaansz S, Ter Meulen S, Pronk LM, Grijpink-Ongering LG, Bruining A, Gittelman RM, Warren S, van Tinteren H, Peeper DS, Haanen JBAG, van Akkooi ACJ, Schumacher TN. Blank CU, et al. Among authors: schumacher tn. Nat Med. 2018 Nov;24(11):1655-1661. doi: 10.1038/s41591-018-0198-0. Epub 2018 Oct 8. Nat Med. 2018. PMID: 30297911 Clinical Trial.
Low and variable tumor reactivity of the intratumoral TCR repertoire in human cancers.
Scheper W, Kelderman S, Fanchi LF, Linnemann C, Bendle G, de Rooij MAJ, Hirt C, Mezzadra R, Slagter M, Dijkstra K, Kluin RJC, Snaebjornsson P, Milne K, Nelson BH, Zijlmans H, Kenter G, Voest EE, Haanen JBAG, Schumacher TN. Scheper W, et al. Among authors: schumacher tn. Nat Med. 2019 Jan;25(1):89-94. doi: 10.1038/s41591-018-0266-5. Epub 2018 Dec 3. Nat Med. 2019. PMID: 30510250
Tumor organoid-T-cell coculture systems.
Cattaneo CM, Dijkstra KK, Fanchi LF, Kelderman S, Kaing S, van Rooij N, van den Brink S, Schumacher TN, Voest EE. Cattaneo CM, et al. Among authors: schumacher tn. Nat Protoc. 2020 Jan;15(1):15-39. doi: 10.1038/s41596-019-0232-9. Epub 2019 Dec 18. Nat Protoc. 2020. PMID: 31853056 Free PMC article.
Neoadjuvant immunotherapy leads to pathological responses in MMR-proficient and MMR-deficient early-stage colon cancers.
Chalabi M, Fanchi LF, Dijkstra KK, Van den Berg JG, Aalbers AG, Sikorska K, Lopez-Yurda M, Grootscholten C, Beets GL, Snaebjornsson P, Maas M, Mertz M, Veninga V, Bounova G, Broeks A, Beets-Tan RG, de Wijkerslooth TR, van Lent AU, Marsman HA, Nuijten E, Kok NF, Kuiper M, Verbeek WH, Kok M, Van Leerdam ME, Schumacher TN, Voest EE, Haanen JB. Chalabi M, et al. Among authors: schumacher tn. Nat Med. 2020 Apr;26(4):566-576. doi: 10.1038/s41591-020-0805-8. Epub 2020 Apr 6. Nat Med. 2020. PMID: 32251400 Clinical Trial.
Peptide selection by MHC class I molecules.
Schumacher TN, De Bruijn ML, Vernie LN, Kast WM, Melief CJ, Neefjes JJ, Ploegh HL. Schumacher TN, et al. Nature. 1991 Apr 25;350(6320):703-6. doi: 10.1038/350703a0. Nature. 1991. PMID: 1708852
313 results