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Towards error-free profiling of immune repertoires.
Shugay M, Britanova OV, Merzlyak EM, Turchaninova MA, Mamedov IZ, Tuganbaev TR, Bolotin DA, Staroverov DB, Putintseva EV, Plevova K, Linnemann C, Shagin D, Pospisilova S, Lukyanov S, Schumacher TN, Chudakov DM. Shugay M, et al. Among authors: schumacher tn. Nat Methods. 2014 Jun;11(6):653-5. doi: 10.1038/nmeth.2960. Epub 2014 May 4. Nat Methods. 2014. PMID: 24793455
T-cell-receptor gene therapy.
Schumacher TN. Schumacher TN. Nat Rev Immunol. 2002 Jul;2(7):512-9. doi: 10.1038/nri841. Nat Rev Immunol. 2002. PMID: 12094225 Review.
Conditional MHC class I ligands and peptide exchange technology for the human MHC gene products HLA-A1, -A3, -A11, and -B7.
Bakker AH, Hoppes R, Linnemann C, Toebes M, Rodenko B, Berkers CR, Hadrup SR, van Esch WJ, Heemskerk MH, Ovaa H, Schumacher TN. Bakker AH, et al. Among authors: schumacher tn. Proc Natl Acad Sci U S A. 2008 Mar 11;105(10):3825-30. doi: 10.1073/pnas.0709717105. Epub 2008 Feb 28. Proc Natl Acad Sci U S A. 2008. PMID: 18308940 Free PMC article.
Lethal graft-versus-host disease in mouse models of T cell receptor gene therapy.
Bendle GM, Linnemann C, Hooijkaas AI, Bies L, de Witte MA, Jorritsma A, Kaiser AD, Pouw N, Debets R, Kieback E, Uckert W, Song JY, Haanen JB, Schumacher TN. Bendle GM, et al. Among authors: schumacher tn. Nat Med. 2010 May;16(5):565-70, 1p following 570. doi: 10.1038/nm.2128. Epub 2010 Apr 18. Nat Med. 2010. PMID: 20400962
TIL therapy broadens the tumor-reactive CD8(+) T cell compartment in melanoma patients.
Kvistborg P, Shu CJ, Heemskerk B, Fankhauser M, Thrue CA, Toebes M, van Rooij N, Linnemann C, van Buuren MM, Urbanus JH, Beltman JB, Thor Straten P, Li YF, Robbins PF, Besser MJ, Schachter J, Kenter GG, Dudley ME, Rosenberg SA, Haanen JB, Hadrup SR, Schumacher TN. Kvistborg P, et al. Among authors: schumacher tn. Oncoimmunology. 2012 Jul 1;1(4):409-418. doi: 10.4161/onci.18851. Oncoimmunology. 2012. PMID: 22754759 Free PMC article.
Pairing of T-cell receptor chains via emulsion PCR.
Turchaninova MA, Britanova OV, Bolotin DA, Shugay M, Putintseva EV, Staroverov DB, Sharonov G, Shcherbo D, Zvyagin IV, Mamedov IZ, Linnemann C, Schumacher TN, Chudakov DM. Turchaninova MA, et al. Among authors: schumacher tn. Eur J Immunol. 2013 Sep;43(9):2507-15. doi: 10.1002/eji.201343453. Epub 2013 Jun 26. Eur J Immunol. 2013. PMID: 23696157 Free article.
High-throughput identification of antigen-specific TCRs by TCR gene capture.
Linnemann C, Heemskerk B, Kvistborg P, Kluin RJ, Bolotin DA, Chen X, Bresser K, Nieuwland M, Schotte R, Michels S, Gomez-Eerland R, Jahn L, Hombrink P, Legrand N, Shu CJ, Mamedov IZ, Velds A, Blank CU, Haanen JB, Turchaninova MA, Kerkhoven RM, Spits H, Hadrup SR, Heemskerk MH, Blankenstein T, Chudakov DM, Bendle GM, Schumacher TN. Linnemann C, et al. Among authors: schumacher tn. Nat Med. 2013 Nov;19(11):1534-41. doi: 10.1038/nm.3359. Epub 2013 Oct 13. Nat Med. 2013. PMID: 24121928
313 results