Schumacher D - Search Results

1

Targeting FLT3 with a new-generation antibody-drug conjugate in combination with kinase inhibitors for treatment of AML.

Roas M, Vick B, Kasper MA, Able M, Polzer H, Gerlach M, Kremmer E, Hecker JS, Schmitt S, Stengl A, Waller V, Hohmann N, Festini M, Ludwig A, Rohrbacher L, Herold T, Subklewe M, Götze KS, Hackenberger CPR, Schumacher D, Helma-Smets J, Jeremias I, Leonhardt H, Spiekermann K. Roas M, et al. Among authors: schumacher d. Blood. 2023 Mar 2;141(9):1023-1035. doi: 10.1182/blood.2021015246. Blood. 2023. PMID: 35981498 Free article.

2

More than add-on: chemoselective reactions for the synthesis of functional peptides and proteins.

Schumacher D, Hackenberger CP. Schumacher D, et al. Curr Opin Chem Biol. 2014 Oct;22:62-9. doi: 10.1016/j.cbpa.2014.09.018. Epub 2014 Oct 3. Curr Opin Chem Biol. 2014. PMID: 25285752 Review.

3

Versatile and Efficient Site-Specific Protein Functionalization by Tubulin Tyrosine Ligase.

Schumacher D, Helma J, Mann FA, Pichler G, Natale F, Krause E, Cardoso MC, Hackenberger CP, Leonhardt H. Schumacher D, et al. Angew Chem Int Ed Engl. 2015 Nov 9;54(46):13787-91. doi: 10.1002/anie.201505456. Epub 2015 Sep 25. Angew Chem Int Ed Engl. 2015. PMID: 26404067

4

Current Status: Site-Specific Antibody Drug Conjugates.

Schumacher D, Hackenberger CP, Leonhardt H, Helma J. Schumacher D, et al. J Clin Immunol. 2016 May;36 Suppl 1:100-7. doi: 10.1007/s10875-016-0265-6. Epub 2016 Mar 22. J Clin Immunol. 2016. PMID: 27003914 Free PMC article. Review.

5

Broad substrate tolerance of tubulin tyrosine ligase enables one-step site-specific enzymatic protein labeling.

Schumacher D, Lemke O, Helma J, Gerszonowicz L, Waller V, Stoschek T, Durkin PM, Budisa N, Leonhardt H, Keller BG, Hackenberger CPR. Schumacher D, et al. Chem Sci. 2017 May 1;8(5):3471-3478. doi: 10.1039/c7sc00574a. Epub 2017 Mar 20. Chem Sci. 2017. PMID: 28507719 Free PMC article.

6

Cell-permeable nanobodies for targeted immunolabelling and antigen manipulation in living cells.

Herce HD, Schumacher D, Schneider AFL, Ludwig AK, Mann FA, Fillies M, Kasper MA, Reinke S, Krause E, Leonhardt H, Cardoso MC, Hackenberger CPR. Herce HD, et al. Among authors: schumacher d. Nat Chem. 2017 Aug;9(8):762-771. doi: 10.1038/nchem.2811. Epub 2017 Jul 17. Nat Chem. 2017. PMID: 28754949

7

Nanobodies: Chemical Functionalization Strategies and Intracellular Applications.

Schumacher D, Helma J, Schneider AFL, Leonhardt H, Hackenberger CPR. Schumacher D, et al. Angew Chem Int Ed Engl. 2018 Feb 23;57(9):2314-2333. doi: 10.1002/anie.201708459. Epub 2018 Jan 26. Angew Chem Int Ed Engl. 2018. PMID: 28913971 Free PMC article. Review.

8

Tub-Tag Labeling; Chemoenzymatic Incorporation of Unnatural Amino Acids.

Helma J, Leonhardt H, Hackenberger CPR, Schumacher D. Helma J, et al. Among authors: schumacher d. Methods Mol Biol. 2018;1728:67-93. doi: 10.1007/978-1-4939-7574-7_4. Methods Mol Biol. 2018. PMID: 29404991

9

FLEXamers: A Double Tag for Universal Generation of Versatile Peptide-MHC Multimers.

Effenberger M, Stengl A, Schober K, Gerget M, Kampick M, Müller TR, Schumacher D, Helma J, Leonhardt H, Busch DH. Effenberger M, et al. Among authors: schumacher d. J Immunol. 2019 Apr 1;202(7):2164-2171. doi: 10.4049/jimmunol.1801435. Epub 2019 Feb 13. J Immunol. 2019. PMID: 30760621

10

Cysteine-Selective Phosphonamidate Electrophiles for Modular Protein Bioconjugations.

Kasper MA, Glanz M, Stengl A, Penkert M, Klenk S, Sauer T, Schumacher D, Helma J, Krause E, Cardoso MC, Leonhardt H, Hackenberger CPR. Kasper MA, et al. Among authors: schumacher d. Angew Chem Int Ed Engl. 2019 Aug 19;58(34):11625-11630. doi: 10.1002/anie.201814715. Epub 2019 Apr 29. Angew Chem Int Ed Engl. 2019. PMID: 30828930

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