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The 2000HIV study: Design, multi-omics methods and participant characteristics.
Vos WAJW, Groenendijk AL, Blaauw MJT, van Eekeren LE, Navas A, Cleophas MCP, Vadaq N, Matzaraki V, Dos Santos JC, Meeder EMG, Fröberg J, Weijers G, Zhang Y, Fu J, Ter Horst R, Bock C, Knoll R, Aschenbrenner AC, Schultze J, Vanderkerckhove L, Hwandih T, Wonderlich ER, Vemula SV, van der Kolk M, de Vet SCP, Blok WL, Brinkman K, Rokx C, Schellekens AFA, de Mast Q, Joosten LAB, Berrevoets MAH, Stalenhoef JE, Verbon A, van Lunzen J, Netea MG, van der Ven AJAM. Vos WAJW, et al. Among authors: schultze j. Front Immunol. 2022 Dec 20;13:982746. doi: 10.3389/fimmu.2022.982746. eCollection 2022. Front Immunol. 2022. PMID: 36605197 Free PMC article.
Human variation in population-wide gene expression data predicts gene perturbation phenotype.
Bonaguro L, Schulte-Schrepping J, Carraro C, Sun LL, Reiz B, Gemünd I, Saglam A, Rahmouni S, Georges M, Arts P, Hoischen A, Joosten LAB, van de Veerdonk FL, Netea MG, Händler K, Mukherjee S, Ulas T, Schultze JL, Aschenbrenner AC. Bonaguro L, et al. Among authors: schultze jl. iScience. 2022 Oct 12;25(11):105328. doi: 10.1016/j.isci.2022.105328. eCollection 2022 Nov 18. iScience. 2022. PMID: 36310583 Free PMC article.
Author Correction: Transmission of trained immunity and heterologous resistance to infections across generations.
Katzmarski N, Domínguez-Andrés J, Cirovic B, Renieris G, Ciarlo E, Le Roy D, Lepikhov K, Kattler K, Gasparoni G, Händler K, Theis H, Beyer M, van der Meer JWM, Joosten LAB, Walter J, Schultze JL, Roger T, Giamarellos-Bourboulis EJ, Schlitzer A, Netea MG. Katzmarski N, et al. Among authors: schultze jl. Nat Immunol. 2023 Feb;24(2):371-372. doi: 10.1038/s41590-023-01426-z. Nat Immunol. 2023. PMID: 36653441 No abstract available.
Fighting Post-COVID and ME/CFS - development of curative therapies.
Scheibenbogen C, Bellmann-Strobl JT, Heindrich C, Wittke K, Stein E, Franke C, Prüss H, Preßler H, Machule ML, Audebert H, Finke C, Zimmermann HG, Sawitzki B, Meisel C, Toelle M, Krueger A, Aschenbrenner AC, Schultze JL, Beyer MD, Ralser M, Mülleder M, Sander LE, Konietschke F, Paul F, Stojanov S, Bruckert L, Hedderich DM, Knolle F, Riemekasten G, Vehreschild MJGT, Cornely OA, Behrends U, Burock S. Scheibenbogen C, et al. Among authors: schultze jl. Front Med (Lausanne). 2023 Jun 15;10:1194754. doi: 10.3389/fmed.2023.1194754. eCollection 2023. Front Med (Lausanne). 2023. PMID: 37396922 Free PMC article.
Molecular mechanisms and treatment responses of pulmonary fibrosis in severe COVID-19.
Kooistra EJ, Dahm K, van Herwaarden AE, Gerretsen J, Nuesch Germano M, Mauer K, Smeets RL, van der Velde S, van den Berg MJW, van der Hoeven JG, Aschenbrenner AC, Schultze JL, Ulas T, Kox M, Pickkers P. Kooistra EJ, et al. Among authors: schultze jl. Respir Res. 2023 Aug 9;24(1):196. doi: 10.1186/s12931-023-02496-1. Respir Res. 2023. PMID: 37559053 Free PMC article.
BCG vaccination induces innate immune memory in γδ T cells in humans.
Suen TK, Moorlag SJCFM, Li W, de Bree LCJ, Koeken VACM, Mourits VP, Dijkstra H, Lemmers H, Bhat J, Xu CJ, Joosten LAB, Schultze JL, Li Y, Placek K, Netea MG. Suen TK, et al. Among authors: schultze jl. J Leukoc Biol. 2024 Jan 5;115(1):149-163. doi: 10.1093/jleuko/qiad103. J Leukoc Biol. 2024. PMID: 37672677
Chromatin accessibility profiling of targeted cell populations with laser capture microdissection coupled to ATAC-seq.
Carraro C, Bonaguro L, Srinivasa R, van Uelft M, Isakzai V, Schulte-Schrepping J, Gambhir P, Elmzzahi T, Montgomery JV, Hayer H, Li Y, Theis H, Kraut M, Mahbubani KT, Aschenbrenner AC, König I, Fava E, Fried HU, De Domenico E, Beyer M, Saglam A, Schultze JL. Carraro C, et al. Among authors: schultze jl. Cell Rep Methods. 2023 Oct 23;3(10):100598. doi: 10.1016/j.crmeth.2023.100598. Epub 2023 Sep 29. Cell Rep Methods. 2023. PMID: 37776856 Free PMC article.
Severe COVID-19 Is Marked by a Dysregulated Myeloid Cell Compartment.
Schulte-Schrepping J, Reusch N, Paclik D, Baßler K, Schlickeiser S, Zhang B, Krämer B, Krammer T, Brumhard S, Bonaguro L, De Domenico E, Wendisch D, Grasshoff M, Kapellos TS, Beckstette M, Pecht T, Saglam A, Dietrich O, Mei HE, Schulz AR, Conrad C, Kunkel D, Vafadarnejad E, Xu CJ, Horne A, Herbert M, Drews A, Thibeault C, Pfeiffer M, Hippenstiel S, Hocke A, Müller-Redetzky H, Heim KM, Machleidt F, Uhrig A, Bosquillon de Jarcy L, Jürgens L, Stegemann M, Glösenkamp CR, Volk HD, Goffinet C, Landthaler M, Wyler E, Georg P, Schneider M, Dang-Heine C, Neuwinger N, Kappert K, Tauber R, Corman V, Raabe J, Kaiser KM, Vinh MT, Rieke G, Meisel C, Ulas T, Becker M, Geffers R, Witzenrath M, Drosten C, Suttorp N, von Kalle C, Kurth F, Händler K, Schultze JL, Aschenbrenner AC, Li Y, Nattermann J, Sawitzki B, Saliba AE, Sander LE; Deutsche COVID-19 OMICS Initiative (DeCOI). Schulte-Schrepping J, et al. Among authors: schultze jl. Cell. 2020 Sep 17;182(6):1419-1440.e23. doi: 10.1016/j.cell.2020.08.001. Epub 2020 Aug 5. Cell. 2020. PMID: 32810438 Free PMC article.
Systems analysis of human innate immunity in COVID-19.
Müller S, Schultze JL. Müller S, et al. Semin Immunol. 2023 Jul;68:101778. doi: 10.1016/j.smim.2023.101778. Epub 2023 May 22. Semin Immunol. 2023. PMID: 37267758 Free PMC article. Review.
Monocyte-derived alveolar macrophages are key drivers of smoke-induced lung inflammation and tissue remodeling.
Wohnhaas CT, Baßler K, Watson CK, Shen Y, Leparc GG, Tilp C, Heinemann F, Kind D, Stierstorfer B, Delić D, Brunner T, Gantner F, Schultze JL, Viollet C, Baum P. Wohnhaas CT, et al. Among authors: schultze jl. Front Immunol. 2024 Jan 29;15:1325090. doi: 10.3389/fimmu.2024.1325090. eCollection 2024. Front Immunol. 2024. PMID: 38348034 Free PMC article.
409 results