Schultz PJ - Search Results

1

High-throughput screen of natural product extracts in a yeast model of polyglutamine proteotoxicity.

Walter GM, Raveh A, Mok SA, McQuade TJ, Arevang CJ, Schultz PJ, Smith MC, Asare S, Cruz PG, Wisen S, Matainaho T, Sherman DH, Gestwicki JE. Walter GM, et al. Among authors: schultz pj. Chem Biol Drug Des. 2014 Apr;83(4):440-9. doi: 10.1111/cbdd.12259. Chem Biol Drug Des. 2014. PMID: 24636344 Free PMC article.

2

Complementary cell-based high-throughput screens identify novel modulators of the unfolded protein response.

Fribley AM, Cruz PG, Miller JR, Callaghan MU, Cai P, Narula N, Neubig RR, Showalter HD, Larsen SD, Kirchhoff PD, Larsen MJ, Burr DA, Schultz PJ, Jacobs RR, Tamayo-Castillo G, Ron D, Sherman DH, Kaufman RJ. Fribley AM, et al. Among authors: schultz pj. J Biomol Screen. 2011 Sep;16(8):825-35. doi: 10.1177/1087057111414893. Epub 2011 Aug 15. J Biomol Screen. 2011. PMID: 21844328 Free PMC article.

3

Titration-based screening for evaluation of natural product extracts: identification of an aspulvinone family of luciferase inhibitors.

Cruz PG, Auld DS, Schultz PJ, Lovell S, Battaile KP, MacArthur R, Shen M, Tamayo-Castillo G, Inglese J, Sherman DH. Cruz PG, et al. Among authors: schultz pj. Chem Biol. 2011 Nov 23;18(11):1442-52. doi: 10.1016/j.chembiol.2011.08.011. Chem Biol. 2011. PMID: 22118678 Free PMC article.

4

Sekikaic acid and lobaric acid target a dynamic interface of the coactivator CBP/p300.

Majmudar CY, Højfeldt JW, Arevang CJ, Pomerantz WC, Gagnon JK, Schultz PJ, Cesa LC, Doss CH, Rowe SP, Vásquez V, Tamayo-Castillo G, Cierpicki T, Brooks CL 3rd, Sherman DH, Mapp AK. Majmudar CY, et al. Among authors: schultz pj. Angew Chem Int Ed Engl. 2012 Nov 5;51(45):11258-62. doi: 10.1002/anie.201206815. Epub 2012 Oct 8. Angew Chem Int Ed Engl. 2012. PMID: 23042634 Free PMC article.

5

Discovery of potent broad spectrum antivirals derived from marine actinobacteria.

Raveh A, Delekta PC, Dobry CJ, Peng W, Schultz PJ, Blakely PK, Tai AW, Matainaho T, Irani DN, Sherman DH, Miller DJ. Raveh A, et al. Among authors: schultz pj. PLoS One. 2013 Dec 5;8(12):e82318. doi: 10.1371/journal.pone.0082318. eCollection 2013. PLoS One. 2013. PMID: 24349254 Free PMC article.

6

Baulamycins A and B, broad-spectrum antibiotics identified as inhibitors of siderophore biosynthesis in Staphylococcus aureus and Bacillus anthracis.

Tripathi A, Schofield MM, Chlipala GE, Schultz PJ, Yim I, Newmister SA, Nusca TD, Scaglione JB, Hanna PC, Tamayo-Castillo G, Sherman DH. Tripathi A, et al. Among authors: schultz pj. J Am Chem Soc. 2014 Jan 29;136(4):1579-86. doi: 10.1021/ja4115924. Epub 2014 Jan 17. J Am Chem Soc. 2014. PMID: 24401083 Free PMC article.

7

Identification of protein kinase C activation as a novel mechanism for RGS2 protein upregulation through phenotypic screening of natural product extracts.

Raveh A, Schultz PJ, Aschermann L, Carpenter C, Tamayo-Castillo G, Cao S, Clardy J, Neubig RR, Sherman DH, Sjögren B. Raveh A, et al. Among authors: schultz pj. Mol Pharmacol. 2014 Oct;86(4):406-16. doi: 10.1124/mol.114.092403. Epub 2014 Aug 1. Mol Pharmacol. 2014. PMID: 25086086 Free PMC article.

8

The combined use of alphavirus replicons and pseudoinfectious particles for the discovery of antivirals derived from natural products.

Delekta PC, Raveh A, Larsen MJ, Schultz PJ, Tamayo-Castillo G, Sherman DH, Miller DJ. Delekta PC, et al. Among authors: schultz pj. J Biomol Screen. 2015 Jun;20(5):673-80. doi: 10.1177/1087057114564868. Epub 2014 Dec 30. J Biomol Screen. 2015. PMID: 25550354 Free PMC article.

9

Microscale Adaptation of In Vitro Transcription/Translation for High-Throughput Screening of Natural Product Extract Libraries.

Lowell AN, Santoro N, Swaney SM, McQuade TJ, Schultz PJ, Larsen MJ, Sherman DH. Lowell AN, et al. Among authors: schultz pj. Chem Biol Drug Des. 2015 Dec;86(6):1331-8. doi: 10.1111/cbdd.12614. Epub 2015 Jul 25. Chem Biol Drug Des. 2015. PMID: 26147927 Free PMC article.

10

Novel Lobophorins Inhibit Oral Cancer Cell Growth and Induce Atf4- and Chop-Dependent Cell Death in Murine Fibroblasts.

Cruz PG, Fribley AM, Miller JR, Larsen MJ, Schultz PJ, Jacob RT, Tamayo-Castillo G, Kaufman RJ, Sherman DH. Cruz PG, et al. Among authors: schultz pj. ACS Med Chem Lett. 2015 Jul 6;6(8):877-81. doi: 10.1021/acsmedchemlett.5b00127. eCollection 2015 Aug 13. ACS Med Chem Lett. 2015. PMID: 26288688 Free PMC article.

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