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Genomically recoded organisms expand biological functions.
Lajoie MJ, Rovner AJ, Goodman DB, Aerni HR, Haimovich AD, Kuznetsov G, Mercer JA, Wang HH, Carr PA, Mosberg JA, Rohland N, Schultz PG, Jacobson JM, Rinehart J, Church GM, Isaacs FJ. Lajoie MJ, et al. Among authors: schultz pg. Science. 2013 Oct 18;342(6156):357-60. doi: 10.1126/science.1241459. Science. 2013. PMID: 24136966 Free PMC article.
Pharmacological expansion of type 2 alveolar epithelial cells promotes regenerative lower airway repair.
Shao S, Zhang N, Specht GP, You S, Song L, Fu Q, Huang D, You H, Shu J, Domissy A, Li S, Nguyen-Tran V, Joseph SB, Chatterjee AK, Chen JJ, Schultz PG, Bollong MJ. Shao S, et al. Among authors: schultz pg. Proc Natl Acad Sci U S A. 2024 Apr 16;121(16):e2400077121. doi: 10.1073/pnas.2400077121. Epub 2024 Apr 10. Proc Natl Acad Sci U S A. 2024. PMID: 38598345
Discovery of CMX990: A Potent SARS-CoV-2 3CL Protease Inhibitor Bearing a Novel Warhead.
Dayan Elshan NGR, Wolff KC, Riva L, Woods AK, Grabovyi G, Wilson K, Pedroarena J, Ghorai S, Nazarian A, Weiss F, Liu Y, Mazumdar W, Song L, Okwor N, Malvin J, Bakowski MA, Beutler N, Kirkpatrick MG, Gebara-Lamb A, Huang E, Nguyen-Tran VTB, Chi V, Li S, Rogers TF, McNamara CW, Gupta AK, Rahimi A, Chen JJ, Joseph SB, Schultz PG, Chatterjee AK. Dayan Elshan NGR, et al. Among authors: schultz pg. J Med Chem. 2024 Feb 22;67(4):2369-2378. doi: 10.1021/acs.jmedchem.3c01938. Epub 2024 Feb 9. J Med Chem. 2024. PMID: 38335279 Free PMC article.
Pharmacological YAP activation promotes regenerative repair of cutaneous wounds.
Grzelak EM, Elshan NGRD, Shao S, Bulos ML, Joseph SB, Chatterjee AK, Chen JJ, Nguyên-Trân V, Schultz PG, Bollong MJ. Grzelak EM, et al. Among authors: schultz pg. Proc Natl Acad Sci U S A. 2023 Jul 11;120(28):e2305085120. doi: 10.1073/pnas.2305085120. Epub 2023 Jul 3. Proc Natl Acad Sci U S A. 2023. PMID: 37399395 Free PMC article.
S-lactoyl modification of KEAP1 by a reactive glycolytic metabolite activates NRF2 signaling.
Ko Y, Hong M, Lee S, Kumar M, Ibrahim L, Nutsch K, Stanton C, Sondermann P, Sandoval B, Bulos ML, Iaconelli J, Chatterjee AK, Wiseman RL, Schultz PG, Bollong MJ. Ko Y, et al. Among authors: schultz pg. Proc Natl Acad Sci U S A. 2023 May 16;120(20):e2300763120. doi: 10.1073/pnas.2300763120. Epub 2023 May 8. Proc Natl Acad Sci U S A. 2023. PMID: 37155889 Free PMC article.
Christopher T. Walsh: Science, mentorship, and service.
Schultz PG. Schultz PG. Proc Natl Acad Sci U S A. 2023 Mar 7;120(10):e2302075120. doi: 10.1073/pnas.2302075120. Epub 2023 Mar 1. Proc Natl Acad Sci U S A. 2023. PMID: 36857341 Free PMC article. No abstract available.
530 results