Schuler-Metz A - Search Results

1

N¹ -Methylnicotinamide as Biomarker for MATE-Mediated Renal Drug-Drug Interactions: Impact of Cimetidine, Rifampin, Verapamil, and Probenecid.

Müller F, Hohl K, Keller S, Schmidt-Gerets S, Deutsch B, Schuler-Metz A, Fromm MF, Stopfer P, Gessner A. Müller F, et al. Among authors: schuler metz a. Clin Pharmacol Ther. 2023 May;113(5):1070-1079. doi: 10.1002/cpt.2849. Epub 2023 Feb 12. Clin Pharmacol Ther. 2023. PMID: 36636898 Clinical Trial.

2

Influence of sub-chronic selective 11β-hydroxysteroid dehydrogenase 1 inhibition on the hypothalamic-pituitary-adrenal axis in female cynomolgus monkeys.

Hamilton BS, Schoelch C, Schuler-Metz A, Krosky P, Lala DS, Claremon DA, McGeehan GM. Hamilton BS, et al. Among authors: schuler metz a. Eur J Pharmacol. 2016 Oct 15;789:68-74. doi: 10.1016/j.ejphar.2016.07.004. Epub 2016 Jul 5. Eur J Pharmacol. 2016. PMID: 27393460

3

Pharmacological characterization of the selective 11β-hydroxysteroid dehydrogenase 1 inhibitor, BI 135585, a clinical candidate for the treatment of type 2 diabetes.

Hamilton BS, Himmelsbach F, Nar H, Schuler-Metz A, Krosky P, Guo J, Guo R, Meng S, Zhao Y, Lala DS, Zhuang L, Claremon DA, McGeehan GM. Hamilton BS, et al. Among authors: schuler metz a. Eur J Pharmacol. 2015 Jan 5;746:50-5. doi: 10.1016/j.ejphar.2014.10.053. Epub 2014 Nov 8. Eur J Pharmacol. 2015. PMID: 25445047

4

Triple fixed-dose combination empagliflozin, linagliptin, and metformin for patients with type 2 diabetes.

Lingvay I, Beetz N, Sennewald R, Schuler-Metz A, Bertulis J, Loley C, Lang B, Lippert C, Lee J, Manning LS, Terada D. Lingvay I, et al. Among authors: schuler metz a. Postgrad Med. 2020 May;132(4):337-345. doi: 10.1080/00325481.2020.1750228. Epub 2020 May 4. Postgrad Med. 2020. PMID: 32366156 Clinical Trial.

5

Validation of the normal, freely moving Göttingen minipig for pharmacological safety testing.

Markert M, Stubhan M, Mayer K, Trautmann T, Klumpp A, Schuler-Metz A, Schumacher K, Guth B. Markert M, et al. Among authors: schuler metz a. J Pharmacol Toxicol Methods. 2009 Jul-Aug;60(1):79-87. doi: 10.1016/j.vascn.2008.12.004. Epub 2009 May 8. J Pharmacol Toxicol Methods. 2009. PMID: 19427912

6

Discovery of BI 135585, an in vivo efficacious oxazinanone-based 11β hydroxysteroid dehydrogenase type 1 inhibitor.

Zhuang L, Tice CM, Xu Z, Zhao W, Cacatian S, Ye YJ, Singh SB, Lindblom P, McKeever BM, Krosky PM, Zhao Y, Lala D, Kruk BA, Meng S, Howard L, Johnson JA, Bukhtiyarov Y, Panemangalore R, Guo J, Guo R, Himmelsbach F, Hamilton B, Schuler-Metz A, Schauerte H, Gregg R, McGeehan GM, Leftheris K, Claremon DA. Zhuang L, et al. Among authors: schuler metz a. Bioorg Med Chem. 2017 Jul 15;25(14):3649-3657. doi: 10.1016/j.bmc.2017.04.033. Epub 2017 Apr 29. Bioorg Med Chem. 2017. PMID: 28528082

7

Discovery and optimization of adamantyl carbamate inhibitors of 11β-HSD1.

Tice CM, Zhao W, Krosky PM, Kruk BA, Berbaum J, Johnson JA, Bukhtiyarov Y, Panemangalore R, Scott BB, Zhao Y, Bruno JG, Howard L, Togias J, Ye YJ, Singh SB, McKeever BM, Lindblom PR, Guo J, Guo R, Nar H, Schuler-Metz A, Gregg RE, Leftheris K, Harrison RK, McGeehan GM, Zhuang L, Claremon DA. Tice CM, et al. Among authors: schuler metz a. Bioorg Med Chem Lett. 2010 Nov 15;20(22):6725-9. doi: 10.1016/j.bmcl.2010.08.142. Epub 2010 Sep 7. Bioorg Med Chem Lett. 2010. PMID: 20864344

8

Simultaneous determination of nicotine and eight nicotine metabolites in urine of smokers using liquid chromatography-tandem mass spectrometry.

Meger M, Meger-Kossien I, Schuler-Metz A, Janket D, Scherer G. Meger M, et al. Among authors: schuler metz a. J Chromatogr B Analyt Technol Biomed Life Sci. 2002 Oct 5;778(1-2):251-61. doi: 10.1016/s0378-4347(01)00451-0. J Chromatogr B Analyt Technol Biomed Life Sci. 2002. PMID: 12376133

9

Comparison of cytochrome P450 2A6 polymorphism frequencies in Caucasians and African-Americans using a new one-step PCR-RFLP genotyping method.

Paschke T, Riefler M, Schuler-Metz A, Wolz L, Scherer G, McBride CM, Bepler G. Paschke T, et al. Among authors: schuler metz a. Toxicology. 2001 Nov 30;168(3):259-68. doi: 10.1016/s0300-483x(01)00470-x. Toxicology. 2001. PMID: 11684323

10

c-Jun (AP-1) activates BMP-4 transcription in Xenopus embryos.

Knöchel S, Schuler-Metz A, Knöchel W. Knöchel S, et al. Among authors: schuler metz a. Mech Dev. 2000 Nov;98(1-2):29-36. doi: 10.1016/s0925-4773(00)00448-2. Mech Dev. 2000. PMID: 11044605 Free article.

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