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Targeting acetate metabolism: Achilles' nightmare.
Miller KD, Schug ZT. Miller KD, et al. Among authors: schug zt. Br J Cancer. 2021 Jun;124(12):1900-1901. doi: 10.1038/s41416-021-01345-6. Epub 2021 Mar 25. Br J Cancer. 2021. PMID: 33767420 Free PMC article.
Co-Targeting FASN and mTOR Suppresses Uveal Melanoma Growth.
Han A, Mukha D, Chua V, Purwin TJ, Tiago M, Modasia B, Baqai U, Aumiller JL, Bechtel N, Hunter E, Danielson M, Terai M, Wedegaertner PB, Sato T, Landreville S, Davies MA, Kurtenbach S, Harbour JW, Schug ZT, Aplin AE. Han A, et al. Among authors: schug zt. Cancers (Basel). 2023 Jun 30;15(13):3451. doi: 10.3390/cancers15133451. Cancers (Basel). 2023. PMID: 37444561 Free PMC article.
The metabolic fate of acetate in cancer.
Schug ZT, Vande Voorde J, Gottlieb E. Schug ZT, et al. Nat Rev Cancer. 2016 Nov;16(11):708-717. doi: 10.1038/nrc.2016.87. Epub 2016 Aug 26. Nat Rev Cancer. 2016. PMID: 27562461 Free PMC article. Review.
MYC regulates fatty acid metabolism through a multigenic program in claudin-low triple negative breast cancer.
Casciano JC, Perry C, Cohen-Nowak AJ, Miller KD, Vande Voorde J, Zhang Q, Chalmers S, Sandison ME, Liu Q, Hedley A, McBryan T, Tang HY, Gorman N, Beer T, Speicher DW, Adams PD, Liu X, Schlegel R, McCarron JG, Wakelam MJO, Gottlieb E, Kossenkov AV, Schug ZT. Casciano JC, et al. Among authors: schug zt. Br J Cancer. 2020 Mar;122(6):868-884. doi: 10.1038/s41416-019-0711-3. Epub 2020 Jan 16. Br J Cancer. 2020. PMID: 31942031 Free PMC article.
Targeting ACSS2 with a Transition-State Mimetic Inhibits Triple-Negative Breast Cancer Growth.
Miller KD, Pniewski K, Perry CE, Papp SB, Shaffer JD, Velasco-Silva JN, Casciano JC, Aramburu TM, Srikanth YVV, Cassel J, Skordalakes E, Kossenkov AV, Salvino JM, Schug ZT. Miller KD, et al. Among authors: schug zt. Cancer Res. 2021 Mar 1;81(5):1252-1264. doi: 10.1158/0008-5472.CAN-20-1847. Epub 2021 Jan 7. Cancer Res. 2021. PMID: 33414169 Free PMC article.
Targeting glutamine dependence through GLS1 inhibition suppresses ARID1A-inactivated clear cell ovarian carcinoma.
Wu S, Fukumoto T, Lin J, Nacarelli T, Wang Y, Ong D, Liu H, Fatkhutdinov N, Zundell JA, Karakashev S, Zhou W, Schwartz LE, Tang HY, Drapkin R, Liu Q, Huntsman DG, Kossenkov AV, Speicher DW, Schug ZT, Van Dang C, Zhang R. Wu S, et al. Among authors: schug zt. Nat Cancer. 2021 Feb;2(2):189-200. doi: 10.1038/s43018-020-00160-x. Epub 2021 Jan 11. Nat Cancer. 2021. PMID: 34085048 Free PMC article.
44 results