Schroeder CI - Search Results

1

Ant venoms contain vertebrate-selective pain-causing sodium channel toxins.

Robinson SD, Deuis JR, Touchard A, Keramidas A, Mueller A, Schroeder CI, Barassé V, Walker AA, Brinkwirth N, Jami S, Bonnafé E, Treilhou M, Undheim EAB, Schmidt JO, King GF, Vetter I. Robinson SD, et al. Among authors: schroeder ci. Nat Commun. 2023 May 23;14(1):2977. doi: 10.1038/s41467-023-38839-1. Nat Commun. 2023. PMID: 37221205 Free PMC article.

2

Chemical synthesis, 3D structure, and ASIC binding site of the toxin mambalgin-2.

Schroeder CI, Rash LD, Vila-Farrés X, Rosengren KJ, Mobli M, King GF, Alewood PF, Craik DJ, Durek T. Schroeder CI, et al. Angew Chem Int Ed Engl. 2014 Jan 20;53(4):1017-20. doi: 10.1002/anie.201308898. Epub 2013 Dec 9. Angew Chem Int Ed Engl. 2014. PMID: 24323786

3

Membrane-binding properties of gating modifier and pore-blocking toxins: Membrane interaction is not a prerequisite for modification of channel gating.

Deplazes E, Henriques ST, Smith JJ, King GF, Craik DJ, Mark AE, Schroeder CI. Deplazes E, et al. Among authors: schroeder ci. Biochim Biophys Acta. 2016 Apr;1858(4):872-82. doi: 10.1016/j.bbamem.2016.02.002. Epub 2016 Feb 2. Biochim Biophys Acta. 2016. PMID: 26850736 Free article.

4

Development of a μO-Conotoxin Analogue with Improved Lipid Membrane Interactions and Potency for the Analgesic Sodium Channel NaV1.8.

Deuis JR, Dekan Z, Inserra MC, Lee TH, Aguilar MI, Craik DJ, Lewis RJ, Alewood PF, Mobli M, Schroeder CI, Henriques ST, Vetter I. Deuis JR, et al. Among authors: schroeder ci. J Biol Chem. 2016 May 27;291(22):11829-42. doi: 10.1074/jbc.M116.721662. Epub 2016 Mar 29. J Biol Chem. 2016. PMID: 27026701 Free PMC article.

5

Interaction of Tarantula Venom Peptide ProTx-II with Lipid Membranes Is a Prerequisite for Its Inhibition of Human Voltage-gated Sodium Channel NaV1.7.

Henriques ST, Deplazes E, Lawrence N, Cheneval O, Chaousis S, Inserra M, Thongyoo P, King GF, Mark AE, Vetter I, Craik DJ, Schroeder CI. Henriques ST, et al. Among authors: schroeder ci. J Biol Chem. 2016 Aug 12;291(33):17049-65. doi: 10.1074/jbc.M116.729095. Epub 2016 Jun 16. J Biol Chem. 2016. PMID: 27311819 Free PMC article.

6

Gating modifier toxins isolated from spider venom: Modulation of voltage-gated sodium channels and the role of lipid membranes.

Agwa AJ, Peigneur S, Chow CY, Lawrence N, Craik DJ, Tytgat J, King GF, Henriques ST, Schroeder CI. Agwa AJ, et al. Among authors: schroeder ci. J Biol Chem. 2018 Jun 8;293(23):9041-9052. doi: 10.1074/jbc.RA118.002553. Epub 2018 Apr 27. J Biol Chem. 2018. PMID: 29703751 Free PMC article.

7

Efficient Enzymatic Ligation of Inhibitor Cystine Knot Spider Venom Peptides: Using Sortase A To Form Double-Knottins That Probe Voltage-Gated Sodium Channel Na_V1.7.

Agwa AJ, Blomster LV, Craik DJ, King GF, Schroeder CI. Agwa AJ, et al. Among authors: schroeder ci. Bioconjug Chem. 2018 Oct 17;29(10):3309-3319. doi: 10.1021/acs.bioconjchem.8b00505. Epub 2018 Sep 12. Bioconjug Chem. 2018. PMID: 30148615

8

Antiallodynic effects of the selective NaV1.7 inhibitor Pn3a in a mouse model of acute postsurgical pain: evidence for analgesic synergy with opioids and baclofen.

Mueller A, Starobova H, Morgan M, Dekan Z, Cheneval O, Schroeder CI, Alewood PF, Deuis JR, Vetter I. Mueller A, et al. Among authors: schroeder ci. Pain. 2019 Aug;160(8):1766-1780. doi: 10.1097/j.pain.0000000000001567. Pain. 2019. PMID: 31335646

9

Fluorescence Imaging of Peripheral Nerves by a Na_v1.7-Targeted Inhibitor Cystine Knot Peptide.

Gonzales J, Demetrio de Souza Franca P, Jiang Y, Pirovano G, Kossatz S, Guru N, Yarilin D, Agwa AJ, Schroeder CI, Patel SG, Ganly I, King GF, Reiner T. Gonzales J, et al. Among authors: schroeder ci. Bioconjug Chem. 2019 Nov 20;30(11):2879-2888. doi: 10.1021/acs.bioconjchem.9b00612. Epub 2019 Nov 8. Bioconjug Chem. 2019. PMID: 31647222 Free PMC article.

10

Enzymatic Ligation of a Pore Blocker Toxin and a Gating Modifier Toxin: Creating Double-Knotted Peptides with Improved Sodium Channel Na_V1.7 Inhibition.

Tran HNT, Tran P, Deuis JR, Agwa AJ, Zhang AH, Vetter I, Schroeder CI. Tran HNT, et al. Among authors: schroeder ci. Bioconjug Chem. 2020 Jan 15;31(1):64-73. doi: 10.1021/acs.bioconjchem.9b00744. Epub 2019 Dec 16. Bioconjug Chem. 2020. PMID: 31790574

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