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Tim-3 adaptor protein Bat3 is a molecular checkpoint of T cell terminal differentiation and exhaustion.
Zhu C, Dixon KO, Newcomer K, Gu G, Xiao S, Zaghouani S, Schramm MA, Wang C, Zhang H, Goto K, Christian E, Rangachari M, Rosenblatt-Rosen O, Okada H, Mak T, Singer M, Regev A, Kuchroo V. Zhu C, et al. Among authors: schramm ma. Sci Adv. 2021 Apr 30;7(18):eabd2710. doi: 10.1126/sciadv.abd2710. Print 2021 Apr. Sci Adv. 2021. PMID: 33931442 Free PMC article.
TIM-3 restrains anti-tumour immunity by regulating inflammasome activation.
Dixon KO, Tabaka M, Schramm MA, Xiao S, Tang R, Dionne D, Anderson AC, Rozenblatt-Rosen O, Regev A, Kuchroo VK. Dixon KO, et al. Among authors: schramm ma. Nature. 2021 Jul;595(7865):101-106. doi: 10.1038/s41586-021-03626-9. Epub 2021 Jun 9. Nature. 2021. PMID: 34108686 Free PMC article.
Induction of a colitogenic phenotype in Th1-like cells depends on interleukin-23 receptor signaling.
Pawlak M, DeTomaso D, Schnell A, Meyer Zu Horste G, Lee Y, Nyman J, Dionne D, Regan BML, Singh V, Delorey T, Schramm MA, Wang C, Wallrapp A, Burkett PR, Riesenfeld SJ, Anderson AC, Regev A, Xavier RJ, Yosef N, Kuchroo VK. Pawlak M, et al. Among authors: schramm ma. Immunity. 2022 Sep 13;55(9):1663-1679.e6. doi: 10.1016/j.immuni.2022.08.007. Epub 2022 Sep 6. Immunity. 2022. PMID: 36070768 Free PMC article.
21 results