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Mutant desmin substantially perturbs mitochondrial morphology, function and maintenance in skeletal muscle tissue.
Winter L, Wittig I, Peeva V, Eggers B, Heidler J, Chevessier F, Kley RA, Barkovits K, Strecker V, Berwanger C, Herrmann H, Marcus K, Kornblum C, Kunz WS, Schröder R, Clemen CS. Winter L, et al. Among authors: schroder r. Acta Neuropathol. 2016 Sep;132(3):453-73. doi: 10.1007/s00401-016-1592-7. Epub 2016 Jul 8. Acta Neuropathol. 2016. PMID: 27393313 Free PMC article.
Homozygous expression of the myofibrillar myopathy-associated p.W2710X filamin C variant reveals major pathomechanisms of sarcomeric lesion formation.
Schuld J, Orfanos Z, Chevessier F, Eggers B, Heil L, Uszkoreit J, Unger A, Kirfel G, van der Ven PFM, Marcus K, Linke WA, Clemen CS, Schröder R, Fürst DO. Schuld J, et al. Among authors: schroder r. Acta Neuropathol Commun. 2020 Sep 4;8(1):154. doi: 10.1186/s40478-020-01001-9. Acta Neuropathol Commun. 2020. PMID: 32887649 Free PMC article.
N471D WASH complex subunit strumpellin knock-in mice display mild motor and cardiac abnormalities and BPTF and KLHL11 dysregulation in brain tissue.
Clemen CS, Schmidt A, Winter L, Canneva F, Wittig I, Becker L, Coras R, Berwanger C; German Mouse Clinic Consortium; Hofmann A, Eggers B, Marcus K, Gailus-Durner V, Fuchs H, de Angelis MH, Krüger M, von Hörsten S, Eichinger L, Schröder R. Clemen CS, et al. Among authors: schroder r. Neuropathol Appl Neurobiol. 2022 Feb;48(1):e12750. doi: 10.1111/nan.12750. Epub 2021 Aug 12. Neuropathol Appl Neurobiol. 2022. PMID: 34312900
Desmin Knock-Out Cardiomyopathy: A Heart on the Verge of Metabolic Crisis.
Elsnicova B, Hornikova D, Tibenska V, Kolar D, Tlapakova T, Schmid B, Mallek M, Eggers B, Schlötzer-Schrehardt U, Peeva V, Berwanger C, Eberhard B, Durmuş H, Schultheis D, Holtzhausen C, Schork K, Marcus K, Jordan J, Lücke T, van der Ven PFM, Schröder R, Clemen CS, Zurmanova JM. Elsnicova B, et al. Among authors: schroder r. Int J Mol Sci. 2022 Oct 10;23(19):12020. doi: 10.3390/ijms231912020. Int J Mol Sci. 2022. PMID: 36233322 Free PMC article.
CRN2 binds to TIMP4 and MMP14 and promotes perivascular invasion of glioblastoma cells.
Solga R, Behrens J, Ziemann A, Riou A, Berwanger C, Becker L, Garrett L, de Angelis MH, Fischer L, Coras R, Barkovits K, Marcus K, Mahabir E, Eichinger L, Schröder R, Noegel AA, Clemen CS; German Mouse Clinic Consortium. Solga R, et al. Among authors: schroder r. Eur J Cell Biol. 2019 Dec;98(5-8):151046. doi: 10.1016/j.ejcb.2019.151046. Epub 2019 Oct 11. Eur J Cell Biol. 2019. PMID: 31677819
The MyoRobot technology discloses a premature biomechanical decay of skeletal muscle fiber bundles derived from R349P desminopathy mice.
Haug M, Meyer C, Reischl B, Prölß G, Vetter K, Iberl J, Nübler S, Schürmann S, Rupitsch SJ, Heckel M, Pöschel T, Winter L, Herrmann H, Clemen CS, Schröder R, Friedrich O. Haug M, et al. Among authors: schroder r. Sci Rep. 2019 Jul 24;9(1):10769. doi: 10.1038/s41598-019-46723-6. Sci Rep. 2019. PMID: 31341183 Free PMC article.
1,022 results