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Preclinical evaluation of the simultaneous inhibition of MCL-1 and BCL-2 with the combination of S63845 and venetoclax in multiple myeloma.
Algarín EM, Díaz-Tejedor A, Mogollón P, Hernández-García S, Corchete LA, San-Segundo L, Martín-Sánchez M, González-Méndez L, Schoumacher M, Banquet S, Kraus-Berthier L, Kloos I, Derreal A, Halilovic E, Maacke H, Gutiérrez NC, Mateos MV, Paíno T, Garayoa M, Ocio EM. Algarín EM, et al. Among authors: schoumacher m. Haematologica. 2020 Mar;105(3):e116-e120. doi: 10.3324/haematol.2018.212308. Epub 2019 Jul 18. Haematologica. 2020. PMID: 31320555 Free PMC article. No abstract available.
Cotargeting BCL-2 and MCL-1 in high-risk B-ALL.
Moujalled DM, Hanna DT, Hediyeh-Zadeh S, Pomilio G, Brown L, Litalien V, Bartolo R, Fleming S, Chanrion M, Banquet S, Maragno AL, Kraus-Berthier L, Schoumacher M, Mullighan CG, Georgiou A, White CA, Lessene G, Huang DCS, Roberts AW, Geneste O, Rasmussen L, Davis MJ, Ekert PG, Wei A, Ng AP, Khaw SL. Moujalled DM, et al. Among authors: schoumacher m. Blood Adv. 2020 Jun 23;4(12):2762-2767. doi: 10.1182/bloodadvances.2019001416. Blood Adv. 2020. PMID: 32569380 Free PMC article.
Dual inhibition of protein kinase C and p53-MDM2 or PKC and mTORC1 are novel efficient therapeutic approaches for uveal melanoma.
Carita G, Frisch-Dit-Leitz E, Dahmani A, Raymondie C, Cassoux N, Piperno-Neumann S, Némati F, Laurent C, De Koning L, Halilovic E, Jeay S, Wylie A, Emery C, Roman-Roman S, Schoumacher M, Decaudin D. Carita G, et al. Among authors: schoumacher m. Oncotarget. 2016 Jun 7;7(23):33542-56. doi: 10.18632/oncotarget.9552. Oncotarget. 2016. PMID: 27507190 Free PMC article.
Intact TP-53 function is essential for sustaining durable responses to BH3-mimetic drugs in leukemias.
Thijssen R, Diepstraten ST, Moujalled D, Chew E, Flensburg C, Shi MX, Dengler MA, Litalien V, MacRaild S, Chen M, Anstee NS, Reljić B, Gabriel SS, Djajawi TM, Riffkin CD, Aubrey BJ, Chang C, Tai L, Xu Z, Morley T, Pomilio G, Bruedigam C, Kallies A, Stroud DA, Bajel A, Kluck RM, Lane SW, Schoumacher M, Banquet S, Majewski IJ, Strasser A, Roberts AW, Huang DCS, Brown FC, Kelly GL, Wei AH. Thijssen R, et al. Among authors: schoumacher m. Blood. 2021 May 20;137(20):2721-2735. doi: 10.1182/blood.2020010167. Blood. 2021. PMID: 33824975 Free PMC article.
The mTOR inhibitor Everolimus synergizes with the PI3K inhibitor GDC0941 to enhance anti-tumor efficacy in uveal melanoma.
Amirouchene-Angelozzi N, Frisch-Dit-Leitz E, Carita G, Dahmani A, Raymondie C, Liot G, Gentien D, Némati F, Decaudin D, Roman-Roman S, Schoumacher M. Amirouchene-Angelozzi N, et al. Among authors: schoumacher m. Oncotarget. 2016 Apr 26;7(17):23633-46. doi: 10.18632/oncotarget.8054. Oncotarget. 2016. PMID: 26988753 Free PMC article.
Upcoming translational challenges for uveal melanoma.
Amirouchene-Angelozzi N, Schoumacher M, Stern MH, Cassoux N, Desjardins L, Piperno-Neumann S, Lantz O, Roman-Roman S. Amirouchene-Angelozzi N, et al. Among authors: schoumacher m. Br J Cancer. 2015 Nov 3;113(9):1249-53. doi: 10.1038/bjc.2015.269. Epub 2015 Oct 27. Br J Cancer. 2015. PMID: 26505679 Free PMC article. Review.
Upcoming translational challenges for uveal melanoma.
Amirouchene-Angelozzi N, Schoumacher M, Stern MH, Cassoux N, Desjardins L, Piperno-Neumann S, Lantz O, Roman-Roman S. Amirouchene-Angelozzi N, et al. Among authors: schoumacher m. Br J Cancer. 2015 Dec 22;113(12):1746. doi: 10.1038/bjc.2015.456. Br J Cancer. 2015. PMID: 26695554 Free PMC article. No abstract available.
33 results