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Dominant role of DNA methylation over H3K9me3 for IAP silencing in endoderm.
Wang Z, Fan R, Russo A, Cernilogar FM, Nuber A, Schirge S, Shcherbakova I, Dzhilyanova I, Ugur E, Anton T, Richter L, Leonhardt H, Lickert H, Schotta G. Wang Z, et al. Among authors: schotta g. Nat Commun. 2022 Sep 19;13(1):5447. doi: 10.1038/s41467-022-32978-7. Nat Commun. 2022. PMID: 36123357 Free PMC article.
CENP-C facilitates the recruitment of M18BP1 to centromeric chromatin.
Dambacher S, Deng W, Hahn M, Sadic D, Fröhlich J, Nuber A, Hoischen C, Diekmann S, Leonhardt H, Schotta G. Dambacher S, et al. Among authors: schotta g. Nucleus. 2012 Jan-Feb;3(1):101-10. doi: 10.4161/nucl.18955. Nucleus. 2012. PMID: 22540025 Free PMC article.
Suv4-20h2 mediates chromatin compaction and is important for cohesin recruitment to heterochromatin.
Hahn M, Dambacher S, Dulev S, Kuznetsova AY, Eck S, Wörz S, Sadic D, Schulte M, Mallm JP, Maiser A, Debs P, von Melchner H, Leonhardt H, Schermelleh L, Rohr K, Rippe K, Storchova Z, Schotta G. Hahn M, et al. Among authors: schotta g. Genes Dev. 2013 Apr 15;27(8):859-72. doi: 10.1101/gad.210377.112. Epub 2013 Apr 18. Genes Dev. 2013. PMID: 23599346 Free PMC article.
The SUV4-20 inhibitor A-196 verifies a role for epigenetics in genomic integrity.
Bromberg KD, Mitchell TR, Upadhyay AK, Jakob CG, Jhala MA, Comess KM, Lasko LM, Li C, Tuzon CT, Dai Y, Li F, Eram MS, Nuber A, Soni NB, Manaves V, Algire MA, Sweis RF, Torrent M, Schotta G, Sun C, Michaelides MR, Shoemaker AR, Arrowsmith CH, Brown PJ, Santhakumar V, Martin A, Rice JC, Chiang GG, Vedadi M, Barsyte-Lovejoy D, Pappano WN. Bromberg KD, et al. Among authors: schotta g. Nat Chem Biol. 2017 Mar;13(3):317-324. doi: 10.1038/nchembio.2282. Epub 2017 Jan 23. Nat Chem Biol. 2017. PMID: 28114273
Silencing of endogenous retroviruses by heterochromatin.
Groh S, Schotta G. Groh S, et al. Among authors: schotta g. Cell Mol Life Sci. 2017 Jun;74(11):2055-2065. doi: 10.1007/s00018-017-2454-8. Epub 2017 Feb 3. Cell Mol Life Sci. 2017. PMID: 28160052 Review.
85 results