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Specific effects of somatic GATA2 zinc finger mutations on erythroid differentiation.
Redondo Monte E, Leubolt G, Windisch R, Kerbs P, Dutta S, Landspersky T, Istvánffy R, Oostendorp RAJ, Chen-Wichmann L, Herold T, Cusan M, Schotta G, Wichmann C, Greif PA. Redondo Monte E, et al. Among authors: schotta g. Exp Hematol. 2022 Apr;108:26-35. doi: 10.1016/j.exphem.2022.02.002. Epub 2022 Feb 16. Exp Hematol. 2022. PMID: 35181392 Free article.
Loss of KDM6A confers drug resistance in acute myeloid leukemia.
Stief SM, Hanneforth AL, Weser S, Mattes R, Carlet M, Liu WH, Bartoschek MD, Domínguez Moreno H, Oettle M, Kempf J, Vick B, Ksienzyk B, Tizazu B, Rothenberg-Thurley M, Quentmeier H, Hiddemann W, Vosberg S, Greif PA, Metzeler KH, Schotta G, Bultmann S, Jeremias I, Leonhardt H, Spiekermann K. Stief SM, et al. Among authors: schotta g. Leukemia. 2020 Jan;34(1):50-62. doi: 10.1038/s41375-019-0497-6. Epub 2019 Jun 14. Leukemia. 2020. PMID: 31201358 Free PMC article.
Loss-of-function mutations in the histone methyltransferase EZH2 promote chemotherapy resistance in AML.
Kempf JM, Weser S, Bartoschek MD, Metzeler KH, Vick B, Herold T, Völse K, Mattes R, Scholz M, Wange LE, Festini M, Ugur E, Roas M, Weigert O, Bultmann S, Leonhardt H, Schotta G, Hiddemann W, Jeremias I, Spiekermann K. Kempf JM, et al. Among authors: schotta g. Sci Rep. 2021 Mar 12;11(1):5838. doi: 10.1038/s41598-021-84708-6. Sci Rep. 2021. PMID: 33712646 Free PMC article.
SETDB1 is required for intestinal epithelial differentiation and the prevention of intestinal inflammation.
Južnić L, Peuker K, Strigli A, Brosch M, Herrmann A, Häsler R, Koch M, Matthiesen L, Zeissig Y, Löscher BS, Nuber A, Schotta G, Neumeister V, Chavakis T, Kurth T, Lesche M, Dahl A, von Mässenhausen A, Linkermann A, Schreiber S, Aden K, Rosenstiel PC, Franke A, Hampe J, Zeissig S. Južnić L, et al. Among authors: schotta g. Gut. 2021 Mar;70(3):485-498. doi: 10.1136/gutjnl-2020-321339. Epub 2020 Jun 5. Gut. 2021. PMID: 32503845 Free PMC article.
Genome-wide analysis of PDX1 target genes in human pancreatic progenitors.
Wang X, Sterr M, Burtscher I, Chen S, Hieronimus A, Machicao F, Staiger H, Häring HU, Lederer G, Meitinger T, Cernilogar FM, Schotta G, Irmler M, Beckers J, Hrabě de Angelis M, Ray M, Wright CVE, Bakhti M, Lickert H. Wang X, et al. Among authors: schotta g. Mol Metab. 2018 Mar;9:57-68. doi: 10.1016/j.molmet.2018.01.011. Epub 2018 Jan 31. Mol Metab. 2018. PMID: 29396371 Free PMC article.
Point mutations in the PDX1 transactivation domain impair human β-cell development and function.
Wang X, Sterr M, Ansarullah, Burtscher I, Böttcher A, Beckenbauer J, Siehler J, Meitinger T, Häring HU, Staiger H, Cernilogar FM, Schotta G, Irmler M, Beckers J, Wright CVE, Bakhti M, Lickert H. Wang X, et al. Among authors: schotta g. Mol Metab. 2019 Jun;24:80-97. doi: 10.1016/j.molmet.2019.03.006. Epub 2019 Mar 20. Mol Metab. 2019. PMID: 30930126 Free PMC article.
Environmental signals rather than layered ontogeny imprint the function of type 2 conventional dendritic cells in young and adult mice.
Papaioannou NE, Salei N, Rambichler S, Ravi K, Popovic J, Küntzel V, Lehmann CHK, Fiancette R, Salvermoser J, Gajdasik DW, Mettler R, Messerer D, Carrelha J, Ohnmacht C, Haller D, Stumm R, Straub T, Jacobsen SEW, Schulz C, Withers DR, Schotta G, Dudziak D, Schraml BU. Papaioannou NE, et al. Among authors: schotta g. Nat Commun. 2021 Jan 19;12(1):464. doi: 10.1038/s41467-020-20659-2. Nat Commun. 2021. PMID: 33469015 Free PMC article.
CENP-C facilitates the recruitment of M18BP1 to centromeric chromatin.
Dambacher S, Deng W, Hahn M, Sadic D, Fröhlich J, Nuber A, Hoischen C, Diekmann S, Leonhardt H, Schotta G. Dambacher S, et al. Among authors: schotta g. Nucleus. 2012 Jan-Feb;3(1):101-10. doi: 10.4161/nucl.18955. Nucleus. 2012. PMID: 22540025 Free PMC article.
85 results