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Bile acids deoxycholic acid and ursodeoxycholic acid differentially regulate human β-defensin-1 and -2 secretion by colonic epithelial cells.
Lajczak NK, Saint-Criq V, O'Dwyer AM, Perino A, Adorini L, Schoonjans K, Keely SJ. Lajczak NK, et al. Among authors: schoonjans k. FASEB J. 2017 Sep;31(9):3848-3857. doi: 10.1096/fj.201601365R. Epub 2017 May 9. FASEB J. 2017. PMID: 28487283
We conclude that bile acids can differentially regulate colonic epithelial HbetaD expression and secretion and discuss the implications of our findings for intestinal health and disease.-Lajczak, N. K., Saint-Criq, V., O'Dwyer, A. M., Perino, A., Adorini, L., Schoonjans …
We conclude that bile acids can differentially regulate colonic epithelial HbetaD expression and secretion and discuss the implications of o …
Dual farnesoid X receptor/TGR5 agonist INT-767 reduces liver injury in the Mdr2-/- (Abcb4-/-) mouse cholangiopathy model by promoting biliary HCO⁻₃ output.
Baghdasaryan A, Claudel T, Gumhold J, Silbert D, Adorini L, Roda A, Vecchiotti S, Gonzalez FJ, Schoonjans K, Strazzabosco M, Fickert P, Trauner M. Baghdasaryan A, et al. Among authors: schoonjans k. Hepatology. 2011 Oct;54(4):1303-12. doi: 10.1002/hep.24537. Hepatology. 2011. PMID: 22006858 Free PMC article.
Vitamin D and energy homeostasis: of mice and men.
Bouillon R, Carmeliet G, Lieben L, Watanabe M, Perino A, Auwerx J, Schoonjans K, Verstuyf A. Bouillon R, et al. Among authors: schoonjans k. Nat Rev Endocrinol. 2014 Feb;10(2):79-87. doi: 10.1038/nrendo.2013.226. Epub 2013 Nov 19. Nat Rev Endocrinol. 2014. PMID: 24247221 Review.
Another Shp on the horizon for bile acids.
Perino A, Schoonjans K. Perino A, et al. Among authors: schoonjans k. Cell Metab. 2014 Aug 5;20(2):203-5. doi: 10.1016/j.cmet.2014.07.019. Cell Metab. 2014. PMID: 25100060 Free article.
A SIRT7-dependent acetylation switch of GABPβ1 controls mitochondrial function.
Ryu D, Jo YS, Lo Sasso G, Stein S, Zhang H, Perino A, Lee JU, Zeviani M, Romand R, Hottiger MO, Schoonjans K, Auwerx J. Ryu D, et al. Among authors: schoonjans k. Cell Metab. 2014 Nov 4;20(5):856-869. doi: 10.1016/j.cmet.2014.08.001. Epub 2014 Sep 4. Cell Metab. 2014. PMID: 25200183 Free article.
194 results