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Angiopoietin-2-induced blood-brain barrier compromise and increased stroke size are rescued by VE-PTP-dependent restoration of Tie2 signaling.
Gurnik S, Devraj K, Macas J, Yamaji M, Starke J, Scholz A, Sommer K, Di Tacchio M, Vutukuri R, Beck H, Mittelbronn M, Foerch C, Pfeilschifter W, Liebner S, Peters KG, Plate KH, Reiss Y. Gurnik S, et al. Among authors: scholz a. Acta Neuropathol. 2016 May;131(5):753-73. doi: 10.1007/s00401-016-1551-3. Epub 2016 Mar 1. Acta Neuropathol. 2016. PMID: 26932603 Free PMC article.
Endothelial cell-derived angiopoietin-2 is a therapeutic target in treatment-naive and bevacizumab-resistant glioblastoma.
Scholz A, Harter PN, Cremer S, Yalcin BH, Gurnik S, Yamaji M, Di Tacchio M, Sommer K, Baumgarten P, Bähr O, Steinbach JP, Trojan J, Glas M, Herrlinger U, Krex D, Meinhardt M, Weyerbrock A, Timmer M, Goldbrunner R, Deckert M, Braun C, Schittenhelm J, Frueh JT, Ullrich E, Mittelbronn M, Plate KH, Reiss Y. Scholz A, et al. EMBO Mol Med. 2016 Jan 1;8(1):39-57. doi: 10.15252/emmm.201505505. EMBO Mol Med. 2016. PMID: 26666269 Free PMC article.
Netrin-1 expression is an independent prognostic factor for poor patient survival in brain metastases.
Harter PN, Zinke J, Scholz A, Tichy J, Zachskorn C, Kvasnicka HM, Goeppert B, Delloye-Bourgeois C, Hattingen E, Senft C, Steinbach JP, Plate KH, Mehlen P, Schulte D, Mittelbronn M. Harter PN, et al. Among authors: scholz a. PLoS One. 2014 Mar 19;9(3):e92311. doi: 10.1371/journal.pone.0092311. eCollection 2014. PLoS One. 2014. PMID: 24647424 Free PMC article.
Distribution and prognostic relevance of tumor-infiltrating lymphocytes (TILs) and PD-1/PD-L1 immune checkpoints in human brain metastases.
Harter PN, Bernatz S, Scholz A, Zeiner PS, Zinke J, Kiyose M, Blasel S, Beschorner R, Senft C, Bender B, Ronellenfitsch MW, Wikman H, Glatzel M, Meinhardt M, Juratli TA, Steinbach JP, Plate KH, Wischhusen J, Weide B, Mittelbronn M. Harter PN, et al. Among authors: scholz a. Oncotarget. 2015 Dec 1;6(38):40836-49. doi: 10.18632/oncotarget.5696. Oncotarget. 2015. PMID: 26517811 Free PMC article.
488 results