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CaMKII as a Therapeutic Target in Cardiovascular Disease.
Reyes Gaido OE, Nkashama LJ, Schole KL, Wang Q, Umapathi P, Mesubi OO, Konstantinidis K, Luczak ED, Anderson ME. Reyes Gaido OE, et al. Among authors: schole kl. Annu Rev Pharmacol Toxicol. 2023 Jan 20;63:249-272. doi: 10.1146/annurev-pharmtox-051421-111814. Epub 2022 Aug 16. Annu Rev Pharmacol Toxicol. 2023. PMID: 35973713 Free PMC article. Review.
An improved reporter identifies ruxolitinib as a potent and cardioprotective CaMKII inhibitor.
Reyes Gaido OE, Pavlaki N, Granger JM, Mesubi OO, Liu B, Lin BL, Long A, Walker D, Mayourian J, Schole KL, Terrillion CE, Nkashama LJ, Hulsurkar MM, Dorn LE, Ferrero KM, Huganir RL, Müller FU, Wehrens XHT, Liu JO, Luczak ED, Bezzerides VJ, Anderson ME. Reyes Gaido OE, et al. Among authors: schole kl. Sci Transl Med. 2023 Jun 21;15(701):eabq7839. doi: 10.1126/scitranslmed.abq7839. Epub 2023 Jun 21. Sci Transl Med. 2023. PMID: 37343080 Free PMC article.