Schofield CJ - Search Results

1

Metallo-β-lactamase-mediated antimicrobial resistance and progress in inhibitor discovery.

Yang Y, Yan YH, Schofield CJ, McNally A, Zong Z, Li GB. Yang Y, et al. Among authors: schofield cj. Trends Microbiol. 2023 Jul;31(7):735-748. doi: 10.1016/j.tim.2023.01.013. Epub 2023 Feb 27. Trends Microbiol. 2023. PMID: 36858862 Review.

2

Structure, function, and evolution of metallo-β-lactamases from the B3 subgroup-emerging targets to combat antibiotic resistance.

Krco S, Davis SJ, Joshi P, Wilson LA, Monteiro Pedroso M, Douw A, Schofield CJ, Hugenholtz P, Schenk G, Morris MT. Krco S, et al. Among authors: schofield cj. Front Chem. 2023 Jun 20;11:1196073. doi: 10.3389/fchem.2023.1196073. eCollection 2023. Front Chem. 2023. PMID: 37408556 Free PMC article. Review.

3

The catalytic domains of all human KDM5 JmjC demethylases catalyse N-methyl arginine demethylation.

Bonnici J, Oueini R, Salah E, Johansson C, Schofield CJ, Kawamura A. Bonnici J, et al. Among authors: schofield cj. FEBS Lett. 2023 Apr;597(7):933-946. doi: 10.1002/1873-3468.14586. Epub 2023 Feb 7. FEBS Lett. 2023. PMID: 36700827 Free PMC article.

4

Biochemistry of the hypoxia-inducible factor hydroxylases.

Fiorini G, Schofield CJ. Fiorini G, et al. Among authors: schofield cj. Curr Opin Chem Biol. 2024 Apr;79:102428. doi: 10.1016/j.cbpa.2024.102428. Epub 2024 Feb 7. Curr Opin Chem Biol. 2024. PMID: 38330792 Free article. Review.

5

Dioxygen Binding Is Controlled by the Protein Environment in Non-heme Fe^II and 2-Oxoglutarate Oxygenases: A Study on Histone Demethylase PHF8 and an Ethylene-Forming Enzyme.

Chaturvedi SS, Thomas MG, Bathir Jaber Sathik Rifayee S, White W, Wildey J, Warner C, Schofield CJ, Hu J, Hausinger RP, Karabencheva-Christova TG, Christov CZ. Chaturvedi SS, et al. Among authors: schofield cj. Chemistry. 2023 Apr 25;29(24):e202300854. doi: 10.1002/chem.202300854. Epub 2023 Apr 3. Chemistry. 2023. PMID: 37009811

6

Dioxygen Binding Is Controlled by the Protein Environment in Non-heme Fe^II and 2-Oxoglutarate Oxygenases: A Study on Histone Demethylase PHF8 and an Ethylene-Forming Enzyme.

Chaturvedi SS, Thomas MG, Rifayee SBJS, White W, Wildey J, Warner C, Schofield CJ, Hu J, Hausinger RP, Karabencheva-Christova TG, Christov CZ. Chaturvedi SS, et al. Among authors: schofield cj. Chemistry. 2023 Apr 25;29(24):e202300138. doi: 10.1002/chem.202300138. Epub 2023 Feb 13. Chemistry. 2023. PMID: 36701641 Free PMC article.

7

Selective targeting of human TET1 by cyclic peptide inhibitors: Insights from biochemical profiling.

Šimelis K, Saraç H, Salah E, Nishio K, McAllister TE, Corner TP, Tumber A, Belle R, Schofield CJ, Suga H, Kawamura A. Šimelis K, et al. Among authors: schofield cj. Bioorg Med Chem. 2024 Feb 1;99:117597. doi: 10.1016/j.bmc.2024.117597. Epub 2024 Jan 12. Bioorg Med Chem. 2024. PMID: 38262305 Free article.

8

Natural and synthetic 2-oxoglutarate derivatives are substrates for oncogenic variants of human isocitrate dehydrogenase 1 and 2.

Liu X, Reinbold R, Liu S, Herold RA, Rabe P, Duclos S, Yadav RB, Abboud MI, Thieffine S, Armstrong FA, Brewitz L, Schofield CJ. Liu X, et al. Among authors: schofield cj. J Biol Chem. 2023 Feb;299(2):102873. doi: 10.1016/j.jbc.2023.102873. Epub 2023 Jan 5. J Biol Chem. 2023. PMID: 36621625 Free PMC article.

9

Activity-based proteomics uncovers suppressed hydrolases and a neo-functionalised antibacterial enzyme at the plant-pathogen interface.

Sueldo DJ, Godson A, Kaschani F, Krahn D, Kessenbrock T, Buscaill P, Schofield CJ, Kaiser M, van der Hoorn RAL. Sueldo DJ, et al. Among authors: schofield cj. New Phytol. 2024 Jan;241(1):394-408. doi: 10.1111/nph.18857. Epub 2023 Mar 29. New Phytol. 2024. PMID: 36866975 Free PMC article.

10

Structural analysis of the 2-oxoglutarate binding site of the circadian rhythm linked oxygenase JMJD5.

Islam MS, Markoulides M, Chowdhury R, Schofield CJ. Islam MS, et al. Among authors: schofield cj. Sci Rep. 2022 Nov 30;12(1):20680. doi: 10.1038/s41598-022-24154-0. Sci Rep. 2022. PMID: 36450832 Free PMC article.

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