Schofield CJ - Search Results

1

Profiling interactions of vaborbactam with metallo-β-lactamases.

Langley GW, Cain R, Tyrrell JM, Hinchliffe P, Calvopiña K, Tooke CL, Widlake E, Dowson CG, Spencer J, Walsh TR, Schofield CJ, Brem J. Langley GW, et al. Among authors: schofield cj. Bioorg Med Chem Lett. 2019 Aug 1;29(15):1981-1984. doi: 10.1016/j.bmcl.2019.05.031. Epub 2019 May 17. Bioorg Med Chem Lett. 2019. PMID: 31171422 Free PMC article.

2

Mass spectrometry reveals elastase inhibitors from the reactive centre loop of alpha1-antitrypsin.

Wright PA, Rostom AA, Robinson CV, Schofield CJ. Wright PA, et al. Among authors: schofield cj. Bioorg Med Chem Lett. 2000 Jun 5;10(11):1219-21. doi: 10.1016/s0960-894x(00)00194-3. Bioorg Med Chem Lett. 2000. PMID: 10866385

3

The inhibition of metallo-beta-lactamase by thioxo-cephalosporin derivatives.

Tsang WY, Dhanda A, Schofield CJ, Frère JM, Galleni M, Page MI. Tsang WY, et al. Among authors: schofield cj. Bioorg Med Chem Lett. 2004 Apr 5;14(7):1737-9. doi: 10.1016/j.bmcl.2004.01.047. Bioorg Med Chem Lett. 2004. PMID: 15026061

4

Inhibitors of the FEZ-1 metallo-beta-lactamase.

Liénard BM, Horsfall LE, Galleni M, Frère JM, Schofield CJ. Liénard BM, et al. Among authors: schofield cj. Bioorg Med Chem Lett. 2007 Feb 15;17(4):964-8. doi: 10.1016/j.bmcl.2006.11.053. Epub 2006 Nov 18. Bioorg Med Chem Lett. 2007. PMID: 17157014

5

Dynamic combinatorial mass spectrometry leads to metallo-beta-lactamase inhibitors.

Liénard BM, Hüting R, Lassaux P, Galleni M, Frère JM, Schofield CJ. Liénard BM, et al. Among authors: schofield cj. J Med Chem. 2008 Feb 14;51(3):684-8. doi: 10.1021/jm070866g. Epub 2008 Jan 19. J Med Chem. 2008. PMID: 18205296

6

Structural basis for the broad-spectrum inhibition of metallo-beta-lactamases by thiols.

Liénard BM, Garau G, Horsfall L, Karsisiotis AI, Damblon C, Lassaux P, Papamicael C, Roberts GC, Galleni M, Dideberg O, Frère JM, Schofield CJ. Liénard BM, et al. Among authors: schofield cj. Org Biomol Chem. 2008 Jul 7;6(13):2282-94. doi: 10.1039/b802311e. Epub 2008 May 7. Org Biomol Chem. 2008. PMID: 18563261

7

Synthesis and evaluation of 3-(dihydroxyboryl)benzoic acids as D,D-carboxypeptidase R39 inhibitors.

Inglis SR, Zervosen A, Woon EC, Gerards T, Teller N, Fischer DS, Luxen A, Schofield CJ. Inglis SR, et al. Among authors: schofield cj. J Med Chem. 2009 Oct 8;52(19):6097-106. doi: 10.1021/jm9009718. J Med Chem. 2009. PMID: 19731939

8

2-Oxoglutarate analogue inhibitors of prolyl hydroxylase domain 2.

Mecinović J, Loenarz C, Chowdhury R, Schofield CJ. Mecinović J, et al. Among authors: schofield cj. Bioorg Med Chem Lett. 2009 Nov 1;19(21):6192-5. doi: 10.1016/j.bmcl.2009.09.005. Epub 2009 Sep 6. Bioorg Med Chem Lett. 2009. PMID: 19775891

9

Using NMR solvent water relaxation to investigate metalloenzyme-ligand binding interactions.

Leung IK, Flashman E, Yeoh KK, Schofield CJ, Claridge TD. Leung IK, et al. Among authors: schofield cj. J Med Chem. 2010 Jan 28;53(2):867-75. doi: 10.1021/jm901537q. J Med Chem. 2010. PMID: 20025281

10

Structural basis for the interaction of lactivicins with serine beta-lactamases.

Brown T Jr, Charlier P, Herman R, Schofield CJ, Sauvage E. Brown T Jr, et al. Among authors: schofield cj. J Med Chem. 2010 Aug 12;53(15):5890-4. doi: 10.1021/jm100437u. J Med Chem. 2010. PMID: 20593835 Free article.

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