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Linked CD4 + /CD8 + T cell neoantigen vaccination overcomes immune checkpoint blockade resistance and enables tumor regression.
Dolina JS, Lee J, Brightman SE, McArdle S, Hall SM, Thota RR, Lanka M, Premlal ALR, Greenbaum JA, Cohen EEW, Peters B, Schoenberger SP. Dolina JS, et al. Among authors: schoenberger sp. bioRxiv [Preprint]. 2023 May 7:2023.05.06.539290. doi: 10.1101/2023.05.06.539290. bioRxiv. 2023. PMID: 37205330 Free PMC article. Updated. Preprint.
Treatment of pancreatic cancer with irreversible electroporation and intratumoral CD40 antibody stimulates systemic immune responses that inhibit liver metastasis in an orthotopic model.
Shankara Narayanan JS, Hayashi T, Erdem S, McArdle S, Tiriac H, Ray P, Pu M, Mikulski Z, Miller A, Messer K, Carson D, Schoenberger S, White RR. Shankara Narayanan JS, et al. J Immunother Cancer. 2023 Jan;11(1):e006133. doi: 10.1136/jitc-2022-006133. J Immunother Cancer. 2023. PMID: 36634919 Free PMC article.
Intra-tumoral T cells in pediatric brain tumors display clonal expansion and effector properties.
Upadhye A, Meza Landeros KE, Ramírez-Suástegui C, Schmiedel BJ, Woo E, Chee SJ, Malicki D, Coufal NG, Gonda D, Levy ML, Greenbaum JA, Seumois G, Crawford J, Roberts WD, Schoenberger SP, Cheroutre H, Ottensmeier CH, Vijayanand P, Ganesan AP. Upadhye A, et al. Among authors: schoenberger sp. Nat Cancer. 2024 Jan 16. doi: 10.1038/s43018-023-00706-9. Online ahead of print. Nat Cancer. 2024. PMID: 38228835
A functional identification platform reveals frequent, spontaneous neoantigen-specific T cell responses in patients with cancer.
Miller AM, Koşaloğlu-Yalçın Z, Westernberg L, Montero L, Bahmanof M, Frentzen A, Lanka M, Logandha Ramamoorthy Premlal A, Seumois G, Greenbaum J, Brightman SE, Soria Zavala K, Thota RR, Naradikian MS, Makani SS, Lippman SM, Sette A, Cohen EEW, Peters B, Schoenberger SP. Miller AM, et al. Among authors: schoenberger sp. Sci Transl Med. 2024 Feb 28;16(736):eabj9905. doi: 10.1126/scitranslmed.abj9905. Epub 2024 Feb 28. Sci Transl Med. 2024. PMID: 38416845
Author Correction: Neoantigen-specific stem cell memory-like CD4+ T cells mediate CD8+ T cell-dependent immunotherapy of MHC class II-negative solid tumors.
Brightman SE, Becker A, Thota RR, Naradikian MS, Chihab L, Zavala KS, Ramamoorthy Premlal AL, Griswold RQ, Dolina JS, Cohen EEW, Miller AM, Peters B, Schoenberger SP. Brightman SE, et al. Among authors: schoenberger sp. Nat Immunol. 2023 Aug;24(8):1391. doi: 10.1038/s41590-023-01591-1. Nat Immunol. 2023. PMID: 37464051 Free PMC article. No abstract available.
Neoantigen-specific stem cell memory-like CD4+ T cells mediate CD8+ T cell-dependent immunotherapy of MHC class II-negative solid tumors.
Brightman SE, Becker A, Thota RR, Naradikian MS, Chihab L, Zavala KS, Ramamoorthy Premlal AL, Griswold RQ, Dolina JS, Cohen EEW, Miller AM, Peters B, Schoenberger SP. Brightman SE, et al. Among authors: schoenberger sp. Nat Immunol. 2023 Aug;24(8):1345-1357. doi: 10.1038/s41590-023-01543-9. Epub 2023 Jul 3. Nat Immunol. 2023. PMID: 37400675 Free PMC article.
112 results