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Molecular determinants of ASIC1 modulation by divalent cations.
Sci Rep. 2024 Jan 28;14(1):2320. doi: 10.1038/s41598-024-52845-3.
Sci Rep. 2024.
PMID: 38282035
Free PMC article.
Discovery of a Series of Substituted 1H-((1,2,3-Triazol-4-yl)methoxy)pyrimidines as Brain Penetrants and Potent GluN2B-Selective Negative Allosteric Modulators.
Gelin CF, Stenne B, Coate H, Hiscox A, Soyode-Johnson A, Wall JL, Lord B, Schoellerman J, Coe KJ, Wang K, Alcázar J, Chrovian CC, Dvorak CA, Carruthers NI, Koudriakova T, Balana B, Letavic MA.
Gelin CF, et al. Among authors: schoellerman j.
J Med Chem. 2023 Feb 23;66(4):2877-2892. doi: 10.1021/acs.jmedchem.2c01916. Epub 2023 Feb 9.
J Med Chem. 2023.
PMID: 36757100
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Molecular mechanism and structural basis of small-molecule modulation of the gating of acid-sensing ion channel 1.
Liu Y, Ma J, DesJarlais RL, Hagan R, Rech J, Lin D, Liu C, Miller R, Schoellerman J, Luo J, Letavic M, Grasberger B, Maher M.
Liu Y, et al. Among authors: schoellerman j.
Commun Biol. 2021 Feb 9;4(1):174. doi: 10.1038/s42003-021-01678-1.
Commun Biol. 2021.
PMID: 33564124
Free PMC article.
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Design, Synthesis, and Preclinical Evaluation of 3-Methyl-6-(5-thiophenyl)-1,3-dihydro-imidazo[4,5-b]pyridin-2-ones as Selective GluN2B Negative Allosteric Modulators for the Treatment of Mood Disorders.
Chrovian CC, Soyode-Johnson A, Stenne B, Pippel DJ, Schoellerman J, Lord B, Needham AS, Xia C, Coe KJ, Sepassi K, Schoetens F, Scott B, Nguyen L, Jiang X, Koudriakova T, Balana B, Letavic MA.
Chrovian CC, et al. Among authors: schoellerman j.
J Med Chem. 2020 Sep 10;63(17):9181-9196. doi: 10.1021/acs.jmedchem.9b02113. Epub 2020 Aug 28.
J Med Chem. 2020.
PMID: 32787105
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1H-Pyrrolo[3,2-b]pyridine GluN2B-Selective Negative Allosteric Modulators.
Chrovian CC, Soyode-Johnson A, Wall JL, Rech JC, Schoellerman J, Lord B, Coe KJ, Carruthers NI, Nguyen L, Jiang X, Koudriakova T, Balana B, Letavic MA.
Chrovian CC, et al. Among authors: schoellerman j.
ACS Med Chem Lett. 2019 Jan 10;10(3):261-266. doi: 10.1021/acsmedchemlett.8b00542. eCollection 2019 Mar 14.
ACS Med Chem Lett. 2019.
PMID: 30891123
Free PMC article.
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Dual actions of Psalmotoxin at ASIC1a and ASIC2a heteromeric channels (ASIC1a/2a).
Liu Y, Hagan R, Schoellerman J.
Liu Y, et al. Among authors: schoellerman j.
Sci Rep. 2018 May 8;8(1):7179. doi: 10.1038/s41598-018-25386-9.
Sci Rep. 2018.
PMID: 29739981
Free PMC article.
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PMCA2 via PSD-95 controls calcium signaling by α7-containing nicotinic acetylcholine receptors on aspiny interneurons.
Gómez-Varela D, Schmidt M, Schoellerman J, Peters EC, Berg DK.
Gómez-Varela D, et al. Among authors: schoellerman j.
J Neurosci. 2012 May 16;32(20):6894-905. doi: 10.1523/JNEUROSCI.5972-11.2012.
J Neurosci. 2012.
PMID: 22593058
Free PMC article.
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Synchronous and asynchronous transmitter release at nicotinic synapses are differentially regulated by postsynaptic PSD-95 proteins.
Neff RA 3rd, Conroy WG, Schoellerman JD, Berg DK.
Neff RA 3rd, et al. Among authors: schoellerman jd.
J Neurosci. 2009 Dec 16;29(50):15770-9. doi: 10.1523/JNEUROSCI.4951-09.2009.
J Neurosci. 2009.
PMID: 20016093
Free PMC article.
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