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MiR-182-3p targets TRF2 and impairs tumor growth of triple-negative breast cancer.
Dinami R, Pompili L, Petti E, Porru M, D'Angelo C, Di Vito S, Rizzo A, Campani V, De Rosa G, Bruna A, Serra V, Mano M, Giacca M, Leonetti C, Ciliberto G, Tarsounas M, Stoppacciaro A, Schoeftner S, Biroccio A. Dinami R, et al. Among authors: schoeftner s. EMBO Mol Med. 2023 Jan 11;15(1):e16033. doi: 10.15252/emmm.202216033. Epub 2022 Nov 25. EMBO Mol Med. 2023. PMID: 36426578 Free PMC article.
Epigenetic silencing of miR-296 and miR-512 ensures hTERT dependent apoptosis protection and telomere maintenance in basal-type breast cancer cells.
Dinami R, Buemi V, Sestito R, Zappone A, Ciani Y, Mano M, Petti E, Sacconi A, Blandino G, Giacca M, Piazza S, Benetti R, Schoeftner S. Dinami R, et al. Among authors: schoeftner s. Oncotarget. 2017 Sep 23;8(56):95674-95691. doi: 10.18632/oncotarget.21180. eCollection 2017 Nov 10. Oncotarget. 2017. PMID: 29221158 Free PMC article.
miR-155 drives telomere fragility in human breast cancer by targeting TRF1.
Dinami R, Ercolani C, Petti E, Piazza S, Ciani Y, Sestito R, Sacconi A, Biagioni F, le Sage C, Agami R, Benetti R, Mottolese M, Schneider C, Blandino G, Schoeftner S. Dinami R, et al. Among authors: schoeftner s. Cancer Res. 2014 Aug 1;74(15):4145-56. doi: 10.1158/0008-5472.CAN-13-2038. Epub 2014 May 29. Cancer Res. 2014. PMID: 24876105
SFPQ and NONO suppress RNA:DNA-hybrid-related telomere instability.
Petti E, Buemi V, Zappone A, Schillaci O, Broccia PV, Dinami R, Matteoni S, Benetti R, Schoeftner S. Petti E, et al. Among authors: schoeftner s. Nat Commun. 2019 Mar 1;10(1):1001. doi: 10.1038/s41467-019-08863-1. Nat Commun. 2019. PMID: 30824709 Free PMC article.
Role of TRF2 in the assembly of telomeric chromatin.
Benetti R, Schoeftner S, Muñoz P, Blasco MA. Benetti R, et al. Among authors: schoeftner s. Cell Cycle. 2008 Nov 1;7(21):3461-8. doi: 10.4161/cc.7.21.7013. Epub 2008 Nov 12. Cell Cycle. 2008. PMID: 18971622
TGS1 mediates 2,2,7-trimethyl guanosine capping of the human telomerase RNA to direct telomerase dependent telomere maintenance.
Buemi V, Schillaci O, Santorsola M, Bonazza D, Broccia PV, Zappone A, Bottin C, Dell'Omo G, Kengne S, Cacchione S, Raffa GD, Piazza S, di Fagagna FD, Benetti R, Cortale M, Zanconati F, Del Sal G, Schoeftner S. Buemi V, et al. Among authors: schoeftner s. Nat Commun. 2022 Apr 28;13(1):2302. doi: 10.1038/s41467-022-29907-z. Nat Commun. 2022. PMID: 35484160 Free PMC article.
Breast Cancer Organoids Model Patient-Specific Response to Drug Treatment.
Campaner E, Zannini A, Santorsola M, Bonazza D, Bottin C, Cancila V, Tripodo C, Bortul M, Zanconati F, Schoeftner S, Del Sal G. Campaner E, et al. Among authors: schoeftner s. Cancers (Basel). 2020 Dec 21;12(12):3869. doi: 10.3390/cancers12123869. Cancers (Basel). 2020. PMID: 33371412 Free PMC article.
29 results