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The Hsp90 machinery facilitates the transport of diphtheria toxin into human cells.
Schuster M, Schnell L, Feigl P, Birkhofer C, Mohr K, Roeder M, Carle S, Langer S, Tippel F, Buchner J, Fischer G, Hausch F, Frick M, Schwan C, Aktories K, Schiene-Fischer C, Barth H. Schuster M, et al. Among authors: schnell l. Sci Rep. 2017 Apr 4;7(1):613. doi: 10.1038/s41598-017-00780-x. Sci Rep. 2017. PMID: 28377614 Free PMC article.
Revisiting an old antibiotic: bacitracin neutralizes binary bacterial toxins and protects cells from intoxication.
Schnell L, Felix I, Müller B, Sadi M, von Bank F, Papatheodorou P, Popoff MR, Aktories K, Waltenberger E, Benz R, Weichbrodt C, Fauler M, Frick M, Barth H. Schnell L, et al. FASEB J. 2019 Apr;33(4):5755-5771. doi: 10.1096/fj.201802453R. Epub 2019 Jan 30. FASEB J. 2019. PMID: 30699302
In conclusion, Bac should be discussed as a therapeutic option against infections with medically relevant toxin-producing bacteria, including C. difficile and B. anthracis, because it inhibits bacterial growth and neutralizes the secreted toxins.-Schnell, L., Felix, …
In conclusion, Bac should be discussed as a therapeutic option against infections with medically relevant toxin-producing bacteria, includin …
CD44 Promotes intoxication by the clostridial iota-family toxins.
Wigelsworth DJ, Ruthel G, Schnell L, Herrlich P, Blonder J, Veenstra TD, Carman RJ, Wilkins TD, Van Nhieu GT, Pauillac S, Gibert M, Sauvonnet N, Stiles BG, Popoff MR, Barth H. Wigelsworth DJ, et al. Among authors: schnell l. PLoS One. 2012;7(12):e51356. doi: 10.1371/journal.pone.0051356. Epub 2012 Dec 7. PLoS One. 2012. PMID: 23236484 Free PMC article.
79 results