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A humanized minipig model for the toxicological testing of therapeutic recombinant antibodies.
Flisikowska T, Egli J, Flisikowski K, Stumbaum M, Küng E, Ebeling M, Schmucki R, Georges G, Singer T, Kurome M, Kessler B, Zakhartchenko V, Wolf E, Weber F, Schnieke A, Iglesias A. Flisikowska T, et al. Among authors: schmucki r. Nat Biomed Eng. 2022 Nov;6(11):1248-1256. doi: 10.1038/s41551-022-00921-2. Epub 2022 Sep 22. Nat Biomed Eng. 2022. PMID: 36138193 Free PMC article.
Functional analysis and transcriptional output of the Göttingen minipig genome.
Heckel T, Schmucki R, Berrera M, Ringshandl S, Badi L, Steiner G, Ravon M, Küng E, Kuhn B, Kratochwil NA, Schmitt G, Kiialainen A, Nowaczyk C, Daff H, Khan AP, Lekolool I, Pelle R, Okoth E, Bishop R, Daubenberger C, Ebeling M, Certa U. Heckel T, et al. Among authors: schmucki r. BMC Genomics. 2015 Nov 14;16:932. doi: 10.1186/s12864-015-2119-7. BMC Genomics. 2015. PMID: 26573612 Free PMC article.
Besca, a single-cell transcriptomics analysis toolkit to accelerate translational research.
Mädler SC, Julien-Laferriere A, Wyss L, Phan M, Sonrel A, Kang ASW, Ulrich E, Schmucki R, Zhang JD, Ebeling M, Badi L, Kam-Thong T, Schwalie PC, Hatje K. Mädler SC, et al. Among authors: schmucki r. NAR Genom Bioinform. 2021 Nov 8;3(4):lqab102. doi: 10.1093/nargab/lqab102. eCollection 2021 Dec. NAR Genom Bioinform. 2021. PMID: 34761219 Free PMC article.
Cargo Delivery into the Brain by in vivo identified Transport Peptides.
Urich E, Schmucki R, Ruderisch N, Kitas E, Certa U, Jacobsen H, Schweitzer C, Bergadano A, Ebeling M, Loetscher H, Freskgård PO. Urich E, et al. Among authors: schmucki r. Sci Rep. 2015 Sep 28;5:14104. doi: 10.1038/srep14104. Sci Rep. 2015. PMID: 26411801 Free PMC article.
Binding to SMN2 pre-mRNA-protein complex elicits specificity for small molecule splicing modifiers.
Sivaramakrishnan M, McCarthy KD, Campagne S, Huber S, Meier S, Augustin A, Heckel T, Meistermann H, Hug MN, Birrer P, Moursy A, Khawaja S, Schmucki R, Berntenis N, Giroud N, Golling S, Tzouros M, Banfai B, Duran-Pacheco G, Lamerz J, Hsiu Liu Y, Luebbers T, Ratni H, Ebeling M, Cléry A, Paushkin S, Krainer AR, Allain FH, Metzger F. Sivaramakrishnan M, et al. Among authors: schmucki r. Nat Commun. 2017 Nov 14;8(1):1476. doi: 10.1038/s41467-017-01559-4. Nat Commun. 2017. PMID: 29133793 Free PMC article.
Targeting RNA structure in SMN2 reverses spinal muscular atrophy molecular phenotypes.
Garcia-Lopez A, Tessaro F, Jonker HRA, Wacker A, Richter C, Comte A, Berntenis N, Schmucki R, Hatje K, Petermann O, Chiriano G, Perozzo R, Sciarra D, Konieczny P, Faustino I, Fournet G, Orozco M, Artero R, Metzger F, Ebeling M, Goekjian P, Joseph B, Schwalbe H, Scapozza L. Garcia-Lopez A, et al. Among authors: schmucki r. Nat Commun. 2018 May 23;9(1):2032. doi: 10.1038/s41467-018-04110-1. Nat Commun. 2018. PMID: 29795225 Free PMC article.
39 results