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Mass Spectrometric Metabolic Fingerprinting of 2-Deoxy-D-Glucose (2-DG)-Induced Inhibition of Glycolysis and Comparative Analysis of Methionine Restriction versus Glucose Restriction under Perfusion Culture in the Murine L929 Model System.
Volland JM, Kaupp J, Schmitz W, Wünsch AC, Balint J, Möllmann M, El-Mesery M, Frackmann K, Peter L, Hartmann S, Kübler AC, Seher A. Volland JM, et al. Among authors: schmitz w. Int J Mol Sci. 2022 Aug 16;23(16):9220. doi: 10.3390/ijms23169220. Int J Mol Sci. 2022. PMID: 36012485 Free PMC article.
A MYC-GCN2-eIF2α negative feedback loop limits protein synthesis to prevent MYC-dependent apoptosis in colorectal cancer.
Schmidt S, Gay D, Uthe FW, Denk S, Paauwe M, Matthes N, Diefenbacher ME, Bryson S, Warrander FC, Erhard F, Ade CP, Baluapuri A, Walz S, Jackstadt R, Ford C, Vlachogiannis G, Valeri N, Otto C, Schülein-Völk C, Maurus K, Schmitz W, Knight JRP, Wolf E, Strathdee D, Schulze A, Germer CT, Rosenwald A, Sansom OJ, Eilers M, Wiegering A. Schmidt S, et al. Among authors: schmitz w. Nat Cell Biol. 2019 Nov;21(11):1413-1424. doi: 10.1038/s41556-019-0408-0. Epub 2019 Nov 4. Nat Cell Biol. 2019. PMID: 31685988 Free PMC article.
LXRα activation and Raf inhibition trigger lethal lipotoxicity in liver cancer.
Rudalska R, Harbig J, Snaebjornsson MT, Klotz S, Zwirner S, Taranets L, Heinzmann F, Kronenberger T, Forster M, Cui W, D'Artista L, Einig E, Hinterleitner M, Schmitz W, Dylawerska A, Kang TW, Poso A, Rosenfeldt MT, Malek NP, Bitzer M, Laufer S, Pichler BJ, Popov N, Schulze A, Zender L, Dauch D. Rudalska R, et al. Among authors: schmitz w. Nat Cancer. 2021 Feb;2(2):201-217. doi: 10.1038/s43018-020-00168-3. Epub 2021 Feb 15. Nat Cancer. 2021. PMID: 35122079
Glycolytic flux control by drugging phosphoglycolate phosphatase.
Jeanclos E, Schlötzer J, Hadamek K, Yuan-Chen N, Alwahsh M, Hollmann R, Fratz S, Yesilyurt-Gerhards D, Frankenbach T, Engelmann D, Keller A, Kaestner A, Schmitz W, Neuenschwander M, Hergenröder R, Sotriffer C, von Kries JP, Schindelin H, Gohla A. Jeanclos E, et al. Among authors: schmitz w. Nat Commun. 2022 Nov 11;13(1):6845. doi: 10.1038/s41467-022-34228-2. Nat Commun. 2022. PMID: 36369173 Free PMC article.
550 results