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Fiber deprivation and microbiome-borne curli shift gut bacterial populations and accelerate disease in a mouse model of Parkinson's disease.
Schmit KJ, Garcia P, Sciortino A, Aho VTE, Pardo Rodriguez B, Thomas MH, Gérardy JJ, Bastero Acha I, Halder R, Cialini C, Heurtaux T, Ostahi I, Busi SB, Grandmougin L, Lowndes T, Singh Y, Martens EC, Mittelbronn M, Buttini M, Wilmes P. Schmit KJ, et al. Cell Rep. 2023 Sep 26;42(9):113071. doi: 10.1016/j.celrep.2023.113071. Epub 2023 Sep 8. Cell Rep. 2023. PMID: 37676767 Free PMC article.
Neurodegeneration and neuroinflammation are linked, but independent of alpha-synuclein inclusions, in a seeding/spreading mouse model of Parkinson's disease.
Garcia P, Jürgens-Wemheuer W, Uriarte Huarte O, Michelucci A, Masuch A, Brioschi S, Weihofen A, Koncina E, Coowar D, Heurtaux T, Glaab E, Balling R, Sousa C, Kaoma T, Nicot N, Pfander T, Schulz-Schaeffer W, Allouche A, Fischer N, Biber K, Kleine-Borgmann F, Mittelbronn M, Ostaszewski M, Schmit KJ, Buttini M. Garcia P, et al. Among authors: schmit kj. Glia. 2022 May;70(5):935-960. doi: 10.1002/glia.24149. Epub 2022 Jan 29. Glia. 2022. PMID: 35092321 Free PMC article.