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Human lungs show limited permissiveness for SARS-CoV-2 due to scarce ACE2 levels but virus-induced expansion of inflammatory macrophages.
Hönzke K, Obermayer B, Mache C, Fatykhova D, Kessler M, Dökel S, Wyler E, Baumgardt M, Löwa A, Hoffmann K, Graff P, Schulze J, Mieth M, Hellwig K, Demir Z, Biere B, Brunotte L, Mecate-Zambrano A, Bushe J, Dohmen M, Hinze C, Elezkurtaj S, Tönnies M, Bauer TT, Eggeling S, Tran HL, Schneider P, Neudecker J, Rückert JC, Schmidt-Ott KM, Busch J, Klauschen F, Horst D, Radbruch H, Radke J, Heppner F, Corman VM, Niemeyer D, Müller MA, Goffinet C, Mothes R, Pascual-Reguant A, Hauser AE, Beule D, Landthaler M, Ludwig S, Suttorp N, Witzenrath M, Gruber AD, Drosten C, Sander LE, Wolff T, Hippenstiel S, Hocke AC. Hönzke K, et al. Eur Respir J. 2022 Dec 1;60(6):2102725. doi: 10.1183/13993003.02725-2021. Print 2022 Dec. Eur Respir J. 2022. PMID: 35728978 Free PMC article.
Tubular Epithelial NF-κB Activity Regulates Ischemic AKI.
Markó L, Vigolo E, Hinze C, Park JK, Roël G, Balogh A, Choi M, Wübken A, Cording J, Blasig IE, Luft FC, Scheidereit C, Schmidt-Ott KM, Schmidt-Ullrich R, Müller DN. Markó L, et al. J Am Soc Nephrol. 2016 Sep;27(9):2658-69. doi: 10.1681/ASN.2015070748. Epub 2016 Jan 28. J Am Soc Nephrol. 2016. PMID: 26823548 Free PMC article.
Critical Illness and Systemic Inflammation Are Key Risk Factors of Severe Acute Kidney Injury in Patients With COVID-19.
Hardenberg JB, Stockmann H, Aigner A, Gotthardt I, Enghard P, Hinze C, Balzer F, Schmidt D, Zickler D, Kruse J, Körner R, Stegemann M, Schneider T, Schumann M, Müller-Redetzky H, Angermair S, Budde K, Weber-Carstens S, Witzenrath M, Treskatsch S, Siegmund B, Spies C, Suttorp N, Rauch G, Eckardt KU, Schmidt-Ott KM. Hardenberg JB, et al. Kidney Int Rep. 2021 Apr;6(4):905-915. doi: 10.1016/j.ekir.2021.01.011. Epub 2021 Feb 2. Kidney Int Rep. 2021. PMID: 33817450 Free PMC article.
Long-term effects of COVID-19 on kidney function.
Enghard P, Hardenberg JH, Stockmann H, Hinze C, Eckardt KU, Schmidt-Ott KM. Enghard P, et al. Lancet. 2021 May 15;397(10287):1806-1807. doi: 10.1016/S0140-6736(21)00880-1. Lancet. 2021. PMID: 33992141 Free PMC article. No abstract available.
Urinary single-cell sequencing captures kidney injury and repair processes in human acute kidney injury.
Klocke J, Kim SJ, Skopnik CM, Hinze C, Boltengagen A, Metzke D, Grothgar E, Prskalo L, Wagner L, Freund P, Görlich N, Muench F, Schmidt-Ott KM, Mashreghi MF, Kocks C, Eckardt KU, Rajewsky N, Enghard P. Klocke J, et al. Kidney Int. 2022 Dec;102(6):1359-1370. doi: 10.1016/j.kint.2022.07.032. Epub 2022 Aug 29. Kidney Int. 2022. PMID: 36049643 Free article.
107 results