Schmidt MS - Search Results

1

Senescent cells promote tissue NAD⁺ decline during ageing via the activation of CD38⁺ macrophages.

Covarrubias AJ, Kale A, Perrone R, Lopez-Dominguez JA, Pisco AO, Kasler HG, Schmidt MS, Heckenbach I, Kwok R, Wiley CD, Wong HS, Gibbs E, Iyer SS, Basisty N, Wu Q, Kim IJ, Silva E, Vitangcol K, Shin KO, Lee YM, Riley R, Ben-Sahra I, Ott M, Schilling B, Scheibye-Knudsen M, Ishihara K, Quake SR, Newman J, Brenner C, Campisi J, Verdin E. Covarrubias AJ, et al. Among authors: schmidt ms. Nat Metab. 2020 Nov;2(11):1265-1283. doi: 10.1038/s42255-020-00305-3. Epub 2020 Nov 16. Nat Metab. 2020. PMID: 33199924 Free PMC article.

2

Nicotinamide riboside is uniquely and orally bioavailable in mice and humans.

Trammell SA, Schmidt MS, Weidemann BJ, Redpath P, Jaksch F, Dellinger RW, Li Z, Abel ED, Migaud ME, Brenner C. Trammell SA, et al. Among authors: schmidt ms. Nat Commun. 2016 Oct 10;7:12948. doi: 10.1038/ncomms12948. Nat Commun. 2016. PMID: 27721479 Free PMC article.

3

Nicotinamide riboside, a form of vitamin B3 and NAD+ precursor, relieves the nociceptive and aversive dimensions of paclitaxel-induced peripheral neuropathy in female rats.

Hamity MV, White SR, Walder RY, Schmidt MS, Brenner C, Hammond DL. Hamity MV, et al. Among authors: schmidt ms. Pain. 2017 May;158(5):962-972. doi: 10.1097/j.pain.0000000000000862. Pain. 2017. PMID: 28346814

4

Nicotinamide Improves Aspects of Healthspan, but Not Lifespan, in Mice.

Mitchell SJ, Bernier M, Aon MA, Cortassa S, Kim EY, Fang EF, Palacios HH, Ali A, Navas-Enamorado I, Di Francesco A, Kaiser TA, Waltz TB, Zhang N, Ellis JL, Elliott PJ, Frederick DW, Bohr VA, Schmidt MS, Brenner C, Sinclair DA, Sauve AA, Baur JA, de Cabo R. Mitchell SJ, et al. Among authors: schmidt ms. Cell Metab. 2018 Mar 6;27(3):667-676.e4. doi: 10.1016/j.cmet.2018.02.001. Cell Metab. 2018. PMID: 29514072 Free PMC article.

5

Pharmacological bypass of NAD⁺ salvage pathway protects neurons from chemotherapy-induced degeneration.

Liu HW, Smith CB, Schmidt MS, Cambronne XA, Cohen MS, Migaud ME, Brenner C, Goodman RH. Liu HW, et al. Among authors: schmidt ms. Proc Natl Acad Sci U S A. 2018 Oct 16;115(42):10654-10659. doi: 10.1073/pnas.1809392115. Epub 2018 Sep 26. Proc Natl Acad Sci U S A. 2018. PMID: 30257945 Free PMC article.

6

Maternal Nicotinamide Riboside Enhances Postpartum Weight Loss, Juvenile Offspring Development, and Neurogenesis of Adult Offspring.

Ear PH, Chadda A, Gumusoglu SB, Schmidt MS, Vogeler S, Malicoat J, Kadel J, Moore MM, Migaud ME, Stevens HE, Brenner C. Ear PH, et al. Among authors: schmidt ms. Cell Rep. 2019 Jan 22;26(4):969-983.e4. doi: 10.1016/j.celrep.2019.01.007. Cell Rep. 2019. PMID: 30673618 Free article.

7

PPM1D mutations silence NAPRT gene expression and confer NAMPT inhibitor sensitivity in glioma.

Fons NR, Sundaram RK, Breuer GA, Peng S, McLean RL, Kalathil AN, Schmidt MS, Carvalho DM, Mackay A, Jones C, Carcaboso ÁM, Nazarian J, Berens ME, Brenner C, Bindra RS. Fons NR, et al. Among authors: schmidt ms. Nat Commun. 2019 Aug 22;10(1):3790. doi: 10.1038/s41467-019-11732-6. Nat Commun. 2019. PMID: 31439867 Free PMC article.

8

Modulation of the cardiac sodium channel Na_V1.5 peak and late currents by NAD⁺ precursors.

Matasic DS, Yoon JY, McLendon JM, Mehdi H, Schmidt MS, Greiner AM, Quinones P, Morgan GM, Boudreau RL, Irani K, Brenner C, London B. Matasic DS, et al. Among authors: schmidt ms. J Mol Cell Cardiol. 2020 Apr;141:70-81. doi: 10.1016/j.yjmcc.2020.01.013. Epub 2020 Mar 21. J Mol Cell Cardiol. 2020. PMID: 32209328 Free PMC article.

9

NAD⁺ Controls Circadian Reprogramming through PER2 Nuclear Translocation to Counter Aging.

Levine DC, Hong H, Weidemann BJ, Ramsey KM, Affinati AH, Schmidt MS, Cedernaes J, Omura C, Braun R, Lee C, Brenner C, Peek CB, Bass J. Levine DC, et al. Among authors: schmidt ms. Mol Cell. 2020 Jun 4;78(5):835-849.e7. doi: 10.1016/j.molcel.2020.04.010. Epub 2020 May 4. Mol Cell. 2020. PMID: 32369735 Free PMC article.

10

Niacin Cures Systemic NAD⁺ Deficiency and Improves Muscle Performance in Adult-Onset Mitochondrial Myopathy.

Pirinen E, Auranen M, Khan NA, Brilhante V, Urho N, Pessia A, Hakkarainen A, Kuula J, Heinonen U, Schmidt MS, Haimilahti K, Piirilä P, Lundbom N, Taskinen MR, Brenner C, Velagapudi V, Pietiläinen KH, Suomalainen A. Pirinen E, et al. Among authors: schmidt ms. Cell Metab. 2020 Jun 2;31(6):1078-1090.e5. doi: 10.1016/j.cmet.2020.04.008. Epub 2020 May 7. Cell Metab. 2020. PMID: 32386566 Free article.

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