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The mitochondrial thioredoxin reductase system (TrxR2) in vascular endothelium controls peroxynitrite levels and tissue integrity.
Kameritsch P, Singer M, Nuernbergk C, Rios N, Reyes AM, Schmidt K, Kirsch J, Schneider H, Müller S, Pogoda K, Cui R, Kirchner T, de Wit C, Lange-Sperandio B, Pohl U, Conrad M, Radi R, Beck H. Kameritsch P, et al. Among authors: schmidt k. Proc Natl Acad Sci U S A. 2021 Feb 16;118(7):e1921828118. doi: 10.1073/pnas.1921828118. Proc Natl Acad Sci U S A. 2021. PMID: 33579817 Free PMC article.
Impaired endothelium-mediated cerebrovascular reactivity promotes anxiety and respiration disorders in mice.
Wenzel J, Hansen CE, Bettoni C, Vogt MA, Lembrich B, Natsagdorj R, Huber G, Brands J, Schmidt K, Assmann JC, Stölting I, Saar K, Sedlacik J, Fiehler J, Ludewig P, Wegmann M, Feller N, Richter M, Müller-Fielitz H, Walther T, König GM, Kostenis E, Raasch W, Hübner N, Gass P, Offermanns S, de Wit C, Wagner CA, Schwaninger M. Wenzel J, et al. Among authors: schmidt k. Proc Natl Acad Sci U S A. 2020 Jan 21;117(3):1753-1761. doi: 10.1073/pnas.1907467117. Epub 2020 Jan 2. Proc Natl Acad Sci U S A. 2020. PMID: 31896584 Free PMC article.
ADAMTS-7 inhibits re-endothelialization of injured arteries and promotes vascular remodeling through cleavage of thrombospondin-1.
Kessler T, Zhang L, Liu Z, Yin X, Huang Y, Wang Y, Fu Y, Mayr M, Ge Q, Xu Q, Zhu Y, Wang X, Schmidt K, de Wit C, Erdmann J, Schunkert H, Aherrahrou Z, Kong W. Kessler T, et al. Among authors: schmidt k. Circulation. 2015 Mar 31;131(13):1191-201. doi: 10.1161/CIRCULATIONAHA.114.014072. Epub 2015 Feb 20. Circulation. 2015. PMID: 25712208
Amplification of EDHF-type vasodilatations in TRPC1-deficient mice.
Schmidt K, Dubrovska G, Nielsen G, Fesüs G, Uhrenholt TR, Hansen PB, Gudermann T, Dietrich A, Gollasch M, de Wit C, Köhler R. Schmidt K, et al. Br J Pharmacol. 2010 Dec;161(8):1722-33. doi: 10.1111/j.1476-5381.2010.00985.x. Br J Pharmacol. 2010. PMID: 20718731 Free PMC article.
3,785 results