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Inducing synthetic lethality for selective targeting of acute myeloid leukemia cells harboring STAG2 mutations.
Subramaniam A, Sandén C, Moura-Castro L, Žemaitis K, Schmiderer L, Baudet A, Bäckström A, Arvidsson E, Hultmark S, Miharada N, Magnusson M, Paulsson K, Fioretos T, Larsson J. Subramaniam A, et al. Among authors: schmiderer l. Haematologica. 2022 Sep 1;107(9):2271-2275. doi: 10.3324/haematol.2021.280303. Haematologica. 2022. PMID: 35638550 Free PMC article. No abstract available.
Combinatorial molecule screening identified a novel diterpene and the BET inhibitor CPI-203 as differentiation inducers of primary acute myeloid leukemia cells.
Hultmark S, Baudet A, Schmiderer L, Prabhala P, Palma-Tortosa S, Sandén C, Fioretos T, Sasidharan R, Larsson C, Lehmann S, Juliusson G, Ek F, Magnusson M. Hultmark S, et al. Among authors: schmiderer l. Haematologica. 2021 Oct 1;106(10):2566-2577. doi: 10.3324/haematol.2020.249177. Haematologica. 2021. PMID: 32855276 Free PMC article.