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Disease modeling of a mutation in α-actinin 2 guides clinical therapy in hypertrophic cardiomyopathy.
Prondzynski M, Lemoine MD, Zech AT, Horváth A, Di Mauro V, Koivumäki JT, Kresin N, Busch J, Krause T, Krämer E, Schlossarek S, Spohn M, Friedrich FW, Münch J, Laufer SD, Redwood C, Volk AE, Hansen A, Mearini G, Catalucci D, Meyer C, Christ T, Patten M, Eschenhagen T, Carrier L. Prondzynski M, et al. Among authors: schlossarek s. EMBO Mol Med. 2022 Aug 8;14(8):e16423. doi: 10.15252/emmm.202216423. EMBO Mol Med. 2022. PMID: 35938313 Free PMC article. No abstract available.
The ubiquitin-proteasome system in cardiac dysfunction.
Mearini G, Schlossarek S, Willis MS, Carrier L. Mearini G, et al. Among authors: schlossarek s. Biochim Biophys Acta. 2008 Dec;1782(12):749-63. doi: 10.1016/j.bbadis.2008.06.009. Epub 2008 Jun 25. Biochim Biophys Acta. 2008. PMID: 18634872 Free article. Review.
Rescue of cardiomyopathy through U7snRNA-mediated exon skipping in Mybpc3-targeted knock-in mice.
Gedicke-Hornung C, Behrens-Gawlik V, Reischmann S, Geertz B, Stimpel D, Weinberger F, Schlossarek S, Précigout G, Braren I, Eschenhagen T, Mearini G, Lorain S, Voit T, Dreyfus PA, Garcia L, Carrier L. Gedicke-Hornung C, et al. Among authors: schlossarek s. EMBO Mol Med. 2013 Jul;5(7):1128-45. doi: 10.1002/emmm.201202168. Epub 2013 May 29. EMBO Mol Med. 2013. PMID: 23716398 Free PMC article.
Ubiquitin-proteasome system and hereditary cardiomyopathies.
Schlossarek S, Frey N, Carrier L. Schlossarek S, et al. J Mol Cell Cardiol. 2014 Jun;71:25-31. doi: 10.1016/j.yjmcc.2013.12.016. Epub 2013 Dec 28. J Mol Cell Cardiol. 2014. PMID: 24380728 Free article. Review.
Mybpc3 gene therapy for neonatal cardiomyopathy enables long-term disease prevention in mice.
Mearini G, Stimpel D, Geertz B, Weinberger F, Krämer E, Schlossarek S, Mourot-Filiatre J, Stoehr A, Dutsch A, Wijnker PJ, Braren I, Katus HA, Müller OJ, Voit T, Eschenhagen T, Carrier L. Mearini G, et al. Among authors: schlossarek s. Nat Commun. 2014 Dec 2;5:5515. doi: 10.1038/ncomms6515. Nat Commun. 2014. PMID: 25463264 Free article.
51 results