Schlessinger J - Search Results

1

Design of protein-binding proteins from the target structure alone.

Cao L, Coventry B, Goreshnik I, Huang B, Sheffler W, Park JS, Jude KM, Marković I, Kadam RU, Verschueren KHG, Verstraete K, Walsh STR, Bennett N, Phal A, Yang A, Kozodoy L, DeWitt M, Picton L, Miller L, Strauch EM, DeBouver ND, Pires A, Bera AK, Halabiya S, Hammerson B, Yang W, Bernard S, Stewart L, Wilson IA, Ruohola-Baker H, Schlessinger J, Lee S, Savvides SN, Garcia KC, Baker D. Cao L, et al. Among authors: schlessinger j. Nature. 2022 May;605(7910):551-560. doi: 10.1038/s41586-022-04654-9. Epub 2022 Mar 24. Nature. 2022. PMID: 35332283 Free PMC article.

2

Protein tyrosine kinase PYK2 involved in Ca(2+)-induced regulation of ion channel and MAP kinase functions.

Lev S, Moreno H, Martinez R, Canoll P, Peles E, Musacchio JM, Plowman GD, Rudy B, Schlessinger J. Lev S, et al. Among authors: schlessinger j. Nature. 1995 Aug 31;376(6543):737-45. doi: 10.1038/376737a0. Nature. 1995. PMID: 7544443

3

Structure of the N-terminal SH3 domain of GRB2 complexed with a peptide from the guanine nucleotide releasing factor Sos.

Terasawa H, Kohda D, Hatanaka H, Tsuchiya S, Ogura K, Nagata K, Ishii S, Mandiyan V, Ullrich A, Schlessinger J, et al. Terasawa H, et al. Among authors: schlessinger j. Nat Struct Biol. 1994 Dec;1(12):891-7. doi: 10.1038/nsb1294-891. Nat Struct Biol. 1994. PMID: 7773778

4

Guanine-nucleotide-releasing factor hSos1 binds to Grb2 and links receptor tyrosine kinases to Ras signalling.

Li N, Batzer A, Daly R, Yajnik V, Skolnik E, Chardin P, Bar-Sagi D, Margolis B, Schlessinger J. Li N, et al. Among authors: schlessinger j. Nature. 1993 May 6;363(6424):85-8. doi: 10.1038/363085a0. Nature. 1993. PMID: 8479541

5

Crystal structure of the PI 3-kinase p85 amino-terminal SH2 domain and its phosphopeptide complexes.

Nolte RT, Eck MJ, Schlessinger J, Shoelson SE, Harrison SC. Nolte RT, et al. Among authors: schlessinger j. Nat Struct Biol. 1996 Apr;3(4):364-74. doi: 10.1038/nsb0496-364. Nat Struct Biol. 1996. PMID: 8599763

6

A role for Pyk2 and Src in linking G-protein-coupled receptors with MAP kinase activation.

Dikic I, Tokiwa G, Lev S, Courtneidge SA, Schlessinger J. Dikic I, et al. Among authors: schlessinger j. Nature. 1996 Oct 10;383(6600):547-50. doi: 10.1038/383547a0. Nature. 1996. PMID: 8849729

7

Structure of a heparin-linked biologically active dimer of fibroblast growth factor.

DiGabriele AD, Lax I, Chen DI, Svahn CM, Jaye M, Schlessinger J, Hendrickson WA. DiGabriele AD, et al. Among authors: schlessinger j. Nature. 1998 Jun 25;393(6687):812-7. doi: 10.1038/31741. Nature. 1998. PMID: 9655399

8

FGF1 and FGF19 reverse diabetes by suppression of the hypothalamic-pituitary-adrenal axis.

Perry RJ, Lee S, Ma L, Zhang D, Schlessinger J, Shulman GI. Perry RJ, et al. Among authors: schlessinger j. Nat Commun. 2015 Apr 28;6:6980. doi: 10.1038/ncomms7980. Nat Commun. 2015. PMID: 25916467 Free PMC article.

9

Data publication with the structural biology data grid supports live analysis.

Meyer PA, Socias S, Key J, Ransey E, Tjon EC, Buschiazzo A, Lei M, Botka C, Withrow J, Neau D, Rajashankar K, Anderson KS, Baxter RH, Blacklow SC, Boggon TJ, Bonvin AM, Borek D, Brett TJ, Caflisch A, Chang CI, Chazin WJ, Corbett KD, Cosgrove MS, Crosson S, Dhe-Paganon S, Di Cera E, Drennan CL, Eck MJ, Eichman BF, Fan QR, Ferré-D'Amaré AR, Fromme JC, Garcia KC, Gaudet R, Gong P, Harrison SC, Heldwein EE, Jia Z, Keenan RJ, Kruse AC, Kvansakul M, McLellan JS, Modis Y, Nam Y, Otwinowski Z, Pai EF, Pereira PJ, Petosa C, Raman CS, Rapoport TA, Roll-Mecak A, Rosen MK, Rudenko G, Schlessinger J, Schwartz TU, Shamoo Y, Sondermann H, Tao YJ, Tolia NH, Tsodikov OV, Westover KD, Wu H, Foster I, Fraser JS, Maia FR, Gonen T, Kirchhausen T, Diederichs K, Crosas M, Sliz P. Meyer PA, et al. Among authors: schlessinger j. Nat Commun. 2016 Mar 7;7:10882. doi: 10.1038/ncomms10882. Nat Commun. 2016. PMID: 26947396 Free PMC article.

10

Structures of β-klotho reveal a 'zip code'-like mechanism for endocrine FGF signalling.

Lee S, Choi J, Mohanty J, Sousa LP, Tome F, Pardon E, Steyaert J, Lemmon MA, Lax I, Schlessinger J. Lee S, et al. Among authors: schlessinger j. Nature. 2018 Jan 25;553(7689):501-505. doi: 10.1038/nature25010. Epub 2018 Jan 17. Nature. 2018. PMID: 29342135 Free PMC article.

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