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Page 1
Identification of a broadly fibrogenic macrophage subset induced by type 3 inflammation.
Fabre T, Barron AMS, Christensen SM, Asano S, Bound K, Lech MP, Wadsworth MH 2nd, Chen X, Wang C, Wang J, McMahon J, Schlerman F, White A, Kravarik KM, Fisher AJ, Borthwick LA, Hart KM, Henderson NC, Wynn TA, Dower K. Fabre T, et al. Among authors: schlerman f. Sci Immunol. 2023 Apr 14;8(82):eadd8945. doi: 10.1126/sciimmunol.add8945. Epub 2023 Apr 7. Sci Immunol. 2023. PMID: 37027478
High resolution molecular and histological analysis of renal disease progression in ZSF1 fa/faCP rats, a model of type 2 diabetic nephropathy.
Dower K, Zhao S, Schlerman FJ, Savary L, Campanholle G, Johnson BG, Xi L, Nguyen V, Zhan Y, Lech MP, Wang J, Nie Q, Karsdal MA, Genovese F, Boucher G, Brown TP, Zhang B, Homer BL, Martinez RV. Dower K, et al. Among authors: schlerman fj. PLoS One. 2017 Jul 26;12(7):e0181861. doi: 10.1371/journal.pone.0181861. eCollection 2017. PLoS One. 2017. PMID: 28746409 Free PMC article.
Thrombospondin-I is a critical modulator in non-alcoholic steatohepatitis (NASH).
Min-DeBartolo J, Schlerman F, Akare S, Wang J, McMahon J, Zhan Y, Syed J, He W, Zhang B, Martinez RV. Min-DeBartolo J, et al. Among authors: schlerman f. PLoS One. 2019 Dec 31;14(12):e0226854. doi: 10.1371/journal.pone.0226854. eCollection 2019. PLoS One. 2019. PMID: 31891606 Free PMC article.
A protein kinase C α and β inhibitor blunts hyperphagia to halt renal function decline and reduces adiposity in a rat model of obesity-driven type 2 diabetes.
Wang J, Casimiro-Garcia A, Johnson BG, Duffen J, Cain M, Savary L, Wang S, Nambiar P, Lech M, Zhao S, Xi L, Zhan Y, Olson J, Stejskal JA, Lin H, Zhang B, Martinez RV, Masek-Hammerman K, Schlerman FJ, Dower K. Wang J, et al. Among authors: schlerman fj. Sci Rep. 2023 Oct 7;13(1):16919. doi: 10.1038/s41598-023-43759-7. Sci Rep. 2023. PMID: 37805649 Free PMC article.
IL-13 blockade reduces lung inflammation after Ascaris suum challenge in cynomolgus monkeys.
Bree A, Schlerman FJ, Wadanoli M, Tchistiakova L, Marquette K, Tan XY, Jacobson BA, Widom A, Cook TA, Wood N, Vunnum S, Krykbaev R, Xu X, Donaldson DD, Goldman SJ, Sypek J, Kasaian MT. Bree A, et al. J Allergy Clin Immunol. 2007 May;119(5):1251-7. doi: 10.1016/j.jaci.2007.02.009. Epub 2007 Mar 26. J Allergy Clin Immunol. 2007. PMID: 17379289
Molecular MR Imaging of Renal Fibrogenesis in Mice.
Chen YC, Waghorn PA, Rosales IA, Arora G, Erstad DJ, Rotile NJ, Jones CM, Ferreira DS, Wei L, Martinez RVP, Schlerman FJ, Wellen J, Fuchs BC, Colvin RB, Ay I, Caravan P. Chen YC, et al. Among authors: schlerman fj. J Am Soc Nephrol. 2023 Jul 1;34(7):1159-1165. doi: 10.1681/ASN.0000000000000148. Epub 2023 Apr 24. J Am Soc Nephrol. 2023. PMID: 37094382
Interleukin-13 neutralization by two distinct receptor blocking mechanisms reduces immunoglobulin E responses and lung inflammation in cynomolgus monkeys.
Kasaian MT, Tan XY, Jin M, Fitz L, Marquette K, Wood N, Cook TA, Lee J, Widom A, Agostinelli R, Bree A, Schlerman FJ, Olland S, Wadanoli M, Sypek J, Gill D, Goldman SJ, Tchistiakova L. Kasaian MT, et al. J Pharmacol Exp Ther. 2008 Jun;325(3):882-92. doi: 10.1124/jpet.108.136515. Epub 2008 Mar 12. J Pharmacol Exp Ther. 2008. PMID: 18337474
Discovery of a Series of Pyrimidine Carboxamides as Inhibitors of Vanin-1.
Casimiro-Garcia A, Allais C, Brennan A, Choi C, Dower G, Farley KA, Fleming M, Flick A, Frisbie RK, Hall J, Hepworth D, Jones H, Knafels JD, Kortum S, Lovering FE, Mathias JP, Mohan S, Morgan PM, Parng C, Parris K, Pullen N, Schlerman F, Stansfield J, Strohbach JW, Vajdos FF, Vincent F, Wang H, Wang X, Webster R, Wright SW. Casimiro-Garcia A, et al. Among authors: schlerman f. J Med Chem. 2022 Jan 13;65(1):757-784. doi: 10.1021/acs.jmedchem.1c01849. Epub 2021 Dec 30. J Med Chem. 2022. PMID: 34967602
15 results