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A multistage sequencing strategy pinpoints novel candidate alleles for Emery-Dreifuss muscular dystrophy and supports gene misregulation as its pathomechanism.
Meinke P, Kerr ARW, Czapiewski R, de Las Heras JI, Dixon CR, Harris E, Kölbel H, Muntoni F, Schara U, Straub V, Schoser B, Wehnert M, Schirmer EC. Meinke P, et al. Among authors: schirmer ec. EBioMedicine. 2020 Jan;51:102587. doi: 10.1016/j.ebiom.2019.11.048. Epub 2019 Dec 17. EBioMedicine. 2020. PMID: 31862442 Free PMC article.
The leukocyte nuclear envelope proteome varies with cell activation and contains novel transmembrane proteins that affect genome architecture.
Korfali N, Wilkie GS, Swanson SK, Srsen V, Batrakou DG, Fairley EA, Malik P, Zuleger N, Goncharevich A, de Las Heras J, Kelly DA, Kerr AR, Florens L, Schirmer EC. Korfali N, et al. Among authors: schirmer ec. Mol Cell Proteomics. 2010 Dec;9(12):2571-85. doi: 10.1074/mcp.M110.002915. Epub 2010 Aug 6. Mol Cell Proteomics. 2010. PMID: 20693407 Free PMC article.
Cancer biology and the nuclear envelope: a convoluted relationship.
de Las Heras JI, Batrakou DG, Schirmer EC. de Las Heras JI, et al. Among authors: schirmer ec. Semin Cancer Biol. 2013 Apr;23(2):125-37. doi: 10.1016/j.semcancer.2012.01.008. Epub 2012 Jan 28. Semin Cancer Biol. 2013. PMID: 22311402 Free article. Review.
The nuclear envelope proteome differs notably between tissues.
Korfali N, Wilkie GS, Swanson SK, Srsen V, de Las Heras J, Batrakou DG, Malik P, Zuleger N, Kerr AR, Florens L, Schirmer EC. Korfali N, et al. Among authors: schirmer ec. Nucleus. 2012 Nov-Dec;3(6):552-64. doi: 10.4161/nucl.22257. Epub 2012 Sep 18. Nucleus. 2012. PMID: 22990521 Free PMC article.
99 results