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Proline-Based Allosteric Inhibitors of Zika and Dengue Virus NS2B/NS3 Proteases.
Millies B, von Hammerstein F, Gellert A, Hammerschmidt S, Barthels F, Göppel U, Immerheiser M, Elgner F, Jung N, Basic M, Kersten C, Kiefer W, Bodem J, Hildt E, Windbergs M, Hellmich UA, Schirmeister T. Millies B, et al. Among authors: schirmeister t. J Med Chem. 2019 Dec 26;62(24):11359-11382. doi: 10.1021/acs.jmedchem.9b01697. Epub 2019 Dec 13. J Med Chem. 2019. PMID: 31769670
Non-peptidic inhibitors of cysteine proteases.
Schirmeister T, Kaeppler U. Schirmeister T, et al. Mini Rev Med Chem. 2003 Jun;3(4):361-73. doi: 10.2174/1389557033488079. Mini Rev Med Chem. 2003. PMID: 12678829 Review.
A new lead for nonpeptidic active-site-directed inhibitors of the severe acute respiratory syndrome coronavirus main protease discovered by a combination of screening and docking methods.
Kaeppler U, Stiefl N, Schiller M, Vicik R, Breuning A, Schmitz W, Rupprecht D, Schmuck C, Baumann K, Ziebuhr J, Schirmeister T. Kaeppler U, et al. Among authors: schirmeister t. J Med Chem. 2005 Nov 3;48(22):6832-42. doi: 10.1021/jm0501782. J Med Chem. 2005. PMID: 16250642
Inhibitors of cysteine proteases.
Vicik R, Busemann M, Baumann K, Schirmeister T. Vicik R, et al. Among authors: schirmeister t. Curr Top Med Chem. 2006;6(4):331-53. doi: 10.2174/156802606776287081. Curr Top Med Chem. 2006. PMID: 16611146 Review.
Identification of a new series of amides as non-covalent proteasome inhibitors.
Scarbaci K, Troiano V, Micale N, Ettari R, Tamborini L, Di Giovanni C, Cerchia C, Grasso S, Novellino E, Schirmeister T, Lavecchia A, Zappalà M. Scarbaci K, et al. Among authors: schirmeister t. Eur J Med Chem. 2014 Apr 9;76:1-9. doi: 10.1016/j.ejmech.2014.01.022. Epub 2014 Jan 25. Eur J Med Chem. 2014. PMID: 24561716
198 results